SCHEMBL28640254

SCHEMBL28640254

CCOC(=O)NN(C(=O)OCC)c1ccc(C(C)(C)C)cc1

nearest known ligand 0.53

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.53
ALDH1A1 P00352 1/20 0.53
KMT2A Q03164 1/20 0.53
SMN1; SMN2 Q16637 2/20 0.49
MAPT P10636 5/20 0.47
LMNA P02545 2/20 0.44
TSHR P16473 2/20 0.43
HTT P42858 1/20 0.39
RAB9A P51151 2/20 0.39
POLB P06746 1/20 0.39
NPC1 O15118 1/20 0.39
HCRTR2 O43614 1/20 0.38
TP53 P04637 1/20 0.38
TACR3 P29371 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10734200 0.85 RAB9A (0.52) MEN1ALDH1A1KMT2ASMN1; SMN2MAPT
SCHEMBL28421212 0.84 KMT2A (0.50) MEN1ALDH1A1KMT2ASMN1; SMN2MAPT
SCHEMBL28631794 0.82 ALDH1A1 (0.51) MEN1ALDH1A1KMT2ASMN1; SMN2MAPT
SCHEMBL10881230 0.82 ALDH1A1 (0.66) MEN1ALDH1A1KMT2ASMN1; SMN2MAPT
SCHEMBL28640296 0.81 KMT2A (0.50) MEN1ALDH1A1KMT2ASMN1; SMN2MAPT
SCHEMBL28651914 0.80 ALDH1A1 (0.56) MEN1ALDH1A1KMT2ASMN1; SMN2MAPT
SCHEMBL3407933 0.78 SMN1; SMN2 (0.50) MEN1ALDH1A1KMT2ASMN1; SMN2MAPT
SCHEMBL10734051 0.78 RAB9A (0.51) MEN1ALDH1A1KMT2ASMN1; SMN2MAPT
SCHEMBL3401397 0.77 SMN1; SMN2 (0.43) MEN1ALDH1A1KMT2ASMN1; SMN2MAPT
SCHEMBL28438516 0.76 MEN1 (0.43) MEN1ALDH1A1KMT2ASMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113248410-B Preparation method of silver-mediated N-aroyl hydrazine compound 湖北工业大学 2023-02-24 CN disclosed
CN-113248410-A Preparation method of silver-mediated N-arylhydrazide compound 湖北工业大学 2021-08-13 CN disclosed