Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MIF | P14174 | 2/20 | 0.41 |
| ▸ | AKT1 | P31749 | 3/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 2/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28420950 | 0.87 | MIF (0.46) | ALDH1A1MAPTMIFAKT1RAB9A | |
| SCHEMBL28421212 | 0.87 | KMT2A (0.50) | SMN1; SMN2ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL3404975 | 0.84 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL3404318 | 0.83 | KMT2A (0.55) | SMN1; SMN2ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL28640254 | 0.78 | MEN1 (0.53) | SMN1; SMN2ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL3401397 | 0.77 | SMN1; SMN2 (0.43) | SMN1; SMN2ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL10734200 | 0.77 | RAB9A (0.52) | SMN1; SMN2ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL28631794 | 0.74 | ALDH1A1 (0.51) | SMN1; SMN2ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL14154007 | 0.74 | AKT1 (0.41) | SMN1; SMN2ALDH1A1MAPTAKT1CA12 | |
| SCHEMBL10565579 | 0.74 | AKT1 (0.49) | SMN1; SMN2ALDH1A1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2252604-A1 | THIAZOLE DERIVATIVE AND USE THEREOF AS VAP-1 INHIBITOR | R-Tech Ueno, Ltd. (JP) | 2010-11-24 | — | — | EP | disclosed |
| WO-2009096609-A1 | THIAZOLE DERIVATIVE AND USE THEREOF AS VAP-1 INHIBITOR | R-TECH UENO, LTD. (JP) | 2009-08-06 | — | — | WO | disclosed |