SCHEMBL28640295

SCHEMBL28640295

O/N=C(\NCc1ccc(Cl)cc1)c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.51
NPSR1 Q6W5P4 2/20 0.51
TSHR P16473 2/20 0.51
MEN1 O00255 3/20 0.50
KMT2A Q03164 3/20 0.50
ALOX12 P18054 2/20 0.50
HPGD P15428 1/20 0.50
PLAAT3 P53816 1/20 0.47
PLAAT5 Q96KN8 1/20 0.47
PLAAT2 Q9NWW9 1/20 0.47
PLAAT4 Q9UL19 1/20 0.47
MAPT P10636 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
LMNA P02545 3/20 0.46
RECQL P46063 2/20 0.46
GAA P10253 1/20 0.44
ADAMTS4 O75173 1/20 0.44
ADAMTS5 Q9UNA0 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28640297 1.00 ALDH1A1 (0.51) ALDH1A1NPSR1TSHRMEN1KMT2A
SCHEMBL28637381 0.93 LMNA (0.52) ALDH1A1NPSR1TSHRMEN1KMT2A
SCHEMBL28637383 0.93 LMNA (0.52) ALDH1A1NPSR1TSHRMEN1KMT2A
SCHEMBL28635370 0.88 ALOX12 (0.50) ALDH1A1MEN1KMT2AALOX12HPGD
SCHEMBL28635369 0.88 ALOX12 (0.50) ALDH1A1MEN1KMT2AALOX12HPGD
SCHEMBL28632720 0.83 SMN1; SMN2 (0.56) ALDH1A1MEN1KMT2AHPGDLMNA
SCHEMBL28635373 0.83 PLA2G1B (0.56) ALDH1A1NPSR1MEN1KMT2AALOX12
SCHEMBL28635375 0.83 PLA2G1B (0.56) ALDH1A1NPSR1MEN1KMT2AALOX12
SCHEMBL28632717 0.83 SMN1; SMN2 (0.56) ALDH1A1MEN1KMT2AHPGDLMNA
SCHEMBL3461078 0.76 HDAC6 (0.70) ALDH1A1TSHRMEN1KMT2AALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113502491-A Electrochemical preparation method of Tioxazafen and atrareum intermediate 湖南大学 2021-10-15 CN disclosed