Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | ABL1 | P00519 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | CSF1R | P07333 | 1/20 | 0.48 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.48 |
| ▸ | KIT | P10721 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30575483 | 1.00 | RXFP1 (0.56) | RXFP1L3MBTL1RAB9ATSHRALDH1A1 | |
| SCHEMBL28642767 | 0.86 | L3MBTL1 (0.61) | RXFP1L3MBTL1RAB9ATSHRALDH1A1 | |
| SCHEMBL30575487 | 0.86 | L3MBTL1 (0.61) | RXFP1L3MBTL1RAB9ATSHRALDH1A1 | |
| SCHEMBL3379277 | 0.85 | ALDH1A1 (0.60) | L3MBTL1RAB9ATSHRALDH1A1POLB | |
| SCHEMBL30575480 | 0.81 | MEN1 (0.65) | L3MBTL1RAB9ATSHRALDH1A1POLB | |
| SCHEMBL28652995 | 0.81 | MEN1 (0.65) | L3MBTL1RAB9ATSHRALDH1A1POLB | |
| SCHEMBL28656203 | 0.81 | RAB9A (0.62) | L3MBTL1RAB9ATSHRALDH1A1POLB | |
| SCHEMBL30575455 | 0.81 | RAB9A (0.62) | L3MBTL1RAB9ATSHRALDH1A1POLB | |
| SCHEMBL28642754 | 0.81 | RAB9A (0.61) | L3MBTL1RAB9ATSHRALDH1A1POLB | |
| SCHEMBL22387485 | 0.81 | ALDH1A1 (0.60) | L3MBTL1RAB9ATSHRALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112812077-B | Benzamide compound, preparation method thereof, pharmaceutical composition and application | 中国科学院上海药物研究所 | 2023-08-22 | — | — | CN | disclosed |
| CN-112812077-A | Benzamide compound and preparation method, pharmaceutical composition and application thereof | 中国科学院上海药物研究所 | 2021-05-18 | — | — | CN | disclosed |