Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | KRAS | P01116 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 4/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26879516 | 0.87 | LMNA (0.67) | LMNAKRASPOLBL3MBTL1ALDH1A1 | |
| SCHEMBL30040021 | 0.80 | CNR2 (0.55) | LMNAIDO1 | |
| SCHEMBL28641161 | 0.80 | CNR2 (0.55) | LMNAIDO1 | |
| SCHEMBL22798889 | 0.79 | ALDH1A1 (0.70) | LMNAKRASPOLBL3MBTL1ALDH1A1 | |
| SCHEMBL31017607 | 0.76 | LMNA (0.56) | LMNAALDH1A1SMN1; SMN2IDO1MEN1 | |
| SCHEMBL22798572 | 0.76 | ALDH1A1 (0.53) | LMNAKRASPOLBL3MBTL1ALDH1A1 | |
| SCHEMBL22813769 | 0.76 | ALDH1A1 (0.53) | LMNAKRASPOLBL3MBTL1ALDH1A1 | |
| SCHEMBL22798571 | 0.76 | ALDH1A1 (0.53) | LMNAKRASPOLBL3MBTL1ALDH1A1 | |
| SCHEMBL28652105 | 0.76 | IDO1 (0.56) | LMNAL3MBTL1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL18611174 | 0.75 | LMNA (0.55) | LMNAIDO1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113480524-B | Alkaloid hamacanthins series derivatives, and preparation method and application thereof | 河北工业大学 | 2022-08-30 | — | — | CN | disclosed |
| CN-113480524-A | Alkaloid hamacanthins series derivatives, and preparation method and application thereof | 河北工业大学 | 2021-10-08 | — | — | CN | disclosed |