Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 3/20 | 0.42 |
| ▸ | CTSL | P07711 | 2/20 | 0.42 |
| ▸ | CTSS | P25774 | 2/20 | 0.42 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.39 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | PREP | P48147 | 3/20 | 0.39 |
| ▸ | CTSK | P43235 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4697017 | 0.76 | CTSS (0.43) | CTSBCTSLCTSSFKBP1ASMN1; SMN2 | |
| SCHEMBL28269300 | 0.74 | KYNU (0.38) | CTSBCTSLCTSSFKBP1ASMN1; SMN2 | |
| SCHEMBL31644278 | 0.73 | CYP3A4 (0.49) | CTSBCTSLCTSSSMN1; SMN2CYP3A4 | |
| SCHEMBL31644660 | 0.73 | CYP3A4 (0.49) | CTSBCTSLCTSSSMN1; SMN2CYP3A4 | |
| SCHEMBL31644337 | 0.73 | CYP3A4 (0.49) | CTSBCTSLCTSSSMN1; SMN2CYP3A4 | |
| SCHEMBL3331774 | 0.72 | CTSL (0.47) | CTSBCTSLCTSSSMN1; SMN2ALDH1A1 | |
| SCHEMBL14743992 | 0.72 | CTSL (0.54) | CTSBCTSLCTSSSMN1; SMN2CYP3A4 | |
| SCHEMBL7440304 | 0.72 | CTSB (0.49) | CTSBCTSLCTSSSMN1; SMN2CYP3A4 | |
| SCHEMBL7440294 | 0.72 | CTSB (0.49) | CTSBCTSLCTSSSMN1; SMN2CYP3A4 | |
| SCHEMBL10191097 | 0.71 | CTSL (0.48) | CTSBCTSLCTSSSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113272297-A | Pyrazole derivatives as H4 antagonist compounds | 赫普泰雅治疗有限公司 | 2021-08-17 | — | — | CN | disclosed |