Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | ABL1 | P00519 | 1/20 | 0.49 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.49 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29382580 | 0.89 | ALDH1A1 (0.59) | ALDH1A1KDM4EPOLBTP53KMT2A | |
| SCHEMBL422152 | 0.89 | ALDH1A1 (0.59) | ALDH1A1KDM4EPOLBTP53KMT2A | |
| SCHEMBL10256187 | 0.88 | ALDH1A1 (0.54) | ALDH1A1KDM4EPOLBTP53KMT2A | |
| SCHEMBL491809 | 0.86 | ALDH1A1 (0.51) | ALDH1A1KDM4EPOLBTP53KMT2A | |
| SCHEMBL491894 | 0.84 | ALDH1A1 (0.55) | ALDH1A1KDM4EPOLBTP53KMT2A | |
| SCHEMBL12585305 | 0.83 | ALDH1A1 (0.57) | ALDH1A1KDM4EPOLBTP53KMT2A | |
| SCHEMBL28461951 | 0.80 | ALDH1A1 (0.49) | ALDH1A1KDM4EPOLBTP53KMT2A | |
| SCHEMBL491822 | 0.80 | ALDH1A1 (0.59) | ALDH1A1KDM4EPOLBTP53KMT2A | |
| SCHEMBL974966 | 0.79 | SLC20A2 (0.59) | ALDH1A1KDM4ETP53KMT2AMEN1 | |
| SCHEMBL490922 | 0.79 | ALDH1A1 (0.60) | ALDH1A1KDM4EPOLBKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113330030-A | Method for determining whether a subject is suitable for treatment with an agonist of soluble guanylate cyclase (sGC) | 拜耳公司 | 2021-08-31 | — | — | CN | claimed |
| CN-113330030-A | Method for determining whether a subject is suitable for treatment with an agonist of soluble guanylate cyclase (sGC) | 拜耳公司 | 2021-08-31 | — | — | CN | disclosed |