Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC20A2 | Q08357 | 1/20 | 0.59 |
| ▸ | SLC20A1 | Q8WUM9 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.55 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.54 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.54 |
| ▸ | SLC10A6 | Q3KNW5 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.52 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL492309 | 0.90 | SLC10A6 (0.61) | ALDH1A1SLC10A2SLC10A1SLC10A6KDM4E | |
| SCHEMBL29382580 | 0.89 | ALDH1A1 (0.59) | ALDH1A1SLC10A2SLC10A1SLC10A6KDM4E | |
| SCHEMBL422152 | 0.89 | ALDH1A1 (0.59) | ALDH1A1SLC10A2SLC10A1SLC10A6KDM4E | |
| SCHEMBL491092 | 0.88 | SLC10A2 (0.57) | ALDH1A1SLC10A2SLC10A1SLC10A6KDM4E | |
| Hydrochloric Acid SCHEMBL971595 | 0.88 | SLC10A2 (0.56) | ALDH1A1SLC10A2SLC10A1SLC10A6KDM4E | |
| SCHEMBL12585305 | 0.86 | ALDH1A1 (0.57) | ALDH1A1SLC10A2SLC10A1SLC10A6KDM4E | |
| SCHEMBL492330 | 0.84 | KMT2A (0.64) | ALDH1A1KDM4ESMN1; SMN2LMNAKMT2A | |
| SCHEMBL492380 | 0.84 | LMNA (0.57) | ALDH1A1SLC10A2SLC10A1SLC10A6KDM4E | |
| SCHEMBL491894 | 0.83 | ALDH1A1 (0.55) | ALDH1A1SLC10A2SLC10A1SLC10A6KDM4E | |
| SCHEMBL5110940 | 0.82 | SLC10A6 (0.68) | SLC20A2SLC20A1SLC10A2SLC10A1SLC10A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2207541-B1 | USE OF SULFONYL-SUBSTITUTED 2-SULFONYLAMINOBENZOIC ACID N-PHENYLAMIDES IN THE TREATMENT OF PAIN | SANOFI AVENTIS DEUTSCHLAND (DE) | 2014-10-29 | — | — | EP | disclosed |
| US-8518998-B2 | Use of sulfonyl-substituted 2-sulfonylaminobenzoic acid N-phenylamides in the treatment of pain | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2013-08-27 | — | — | US | disclosed |
| US-20110021505-A1 | Use of sulfonyl-substituted 2-sulfonylaminobenzoic acid N-phenylamides in the treatment of pain | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2011-01-27 | — | — | US | disclosed |
| EP-2207541-A1 | USE OF SULFONYL-SUBSTITUTED 2-SULFONYLAMINOBENZOIC ACID N-PHENYLAMIDES IN THE TREATMENT OF PAIN | Sanofi-Aventis Deutschland GmbH (DE) | 2010-07-21 | — | — | EP | disclosed |
| WO-2009043495-A1 | USE OF SULFONYL-SUBSTITUTED 2-SULFONYLAMINOBENZOIC ACID N-PHENYLAMIDES IN THE TREATMENT OF PAIN | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2009-04-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110021505-A1 | Use of sulfonyl-substituted 2-sulfonylaminobenzoic acid N-phenylamides in the treatment of pain | SCN1A, SCN2A, CACNA1A | SLC20A2 355/4885SLC20A1 263/4885ALDH1A1 494/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.