Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 1/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | SCD | O00767 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CRHBP | P24387 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propionic Acid SCHEMBL29049218 | 0.89 | HSD17B10 (0.54) | ADRA2CHDAC8HDAC1HDAC6HSD17B10 | |
| SCHEMBL3440796 | 0.88 | ADRA2C (0.72) | ADRA2CHDAC8HDAC1HDAC6HPGD | |
| Bromide SCHEMBL30496129 | 0.86 | ADRA2C (0.70) | ADRA2CHDAC8HDAC1HDAC6HPGD | |
| Malonic Acid SCHEMBL29049213 | 0.81 | HSD17B10 (0.55) | ADRA2CHDAC8HDAC1HDAC6HPGD | |
| Bicarbonate SCHEMBL29049243 | 0.80 | HSD17B10 (0.58) | ADRA2CHDAC8HDAC1HDAC6HPGD | |
| Butyric Acid SCHEMBL29049202 | 0.79 | POLB (0.53) | HDAC8HDAC1HDAC6HSD17B10KMT2A | |
| N-Benzylaniline SCHEMBL11480512 | 0.79 | FFAR1 (0.64) | HDAC8HDAC1HDAC6KMT2AMEN1 | |
| Acetic Acid SCHEMBL29049224 | 0.79 | HSD17B10 (0.56) | ADRA2CHDAC8HDAC1HDAC6HPGD | |
| SCHEMBL8009873 | 0.79 | KDM4E (0.54) | ADRA2CHDAC8HDAC1HDAC6HPGD | |
| Oxalic Acid SCHEMBL29049203 | 0.79 | HSD17B10 (0.56) | ADRA2CHDAC8HDAC1HDAC6HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108026028-B | Treatment of diabetes and metabolic syndrome with novel dual modulators of soluble epoxide hydrolase and peroxisome proliferator-activated receptors | 威斯康星州医药大学股份有限公司 | 2021-11-09 | — | — | CN | disclosed |