Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | PLK1 | P53350 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.50 |
| ▸ | FABP3 | P05413 | 1/20 | 0.49 |
| ▸ | FABP4 | P15090 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.49 |
| ▸ | KDM6B | O15054 | 1/20 | 0.47 |
| ▸ | KDM4A | O75164 | 1/20 | 0.47 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.47 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1715510 | 0.88 | ADRA2C (0.63) | KDM4EKMT2APLK1POLBL3MBTL1 | |
| Bicarbonate SCHEMBL29049243 | 0.82 | HSD17B10 (0.58) | HSD17B10KMT2AHDAC1HDAC8HDAC6 | |
| SCHEMBL1903512 | 0.81 | KDM4E (0.50) | KDM4EKMT2APLK1HDAC1HDAC8 | |
| Oxalic Acid SCHEMBL29049203 | 0.81 | HSD17B10 (0.56) | HSD17B10KMT2AHDAC1HDAC8HDAC6 | |
| SCHEMBL12427631 | 0.81 | PLK1 (0.67) | KDM4EHSD17B10KMT2APLK1HDAC1 | |
| Acetic Acid SCHEMBL29049224 | 0.81 | HSD17B10 (0.56) | HSD17B10KMT2AHDAC1HDAC8HDAC6 | |
| Phthalic Acid SCHEMBL29049255 | 0.80 | KMT2A (0.61) | KDM4EHSD17B10KMT2APLK1HPGD | |
| SCHEMBL30358562 | 0.80 | CA12 (0.57) | HSD17B10KMT2APLK1HDAC1HDAC8 | |
| Benzoic Acid SCHEMBL29049235 | 0.80 | HSD17B10 (0.56) | HSD17B10KMT2AHDAC1HDAC8HDAC6 | |
| Terephthalic Acid SCHEMBL29049219 | 0.80 | HSD17B10 (0.60) | HSD17B10KMT2AHDAC1HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000027394-A1 | ACTIVATORS OF SOLUBLE GUANYLATE CYCLASE | UNIVERSITY COLLEGE LONDON (GB) | 2000-05-18 | — | — | WO | disclosed |