Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.45 |
| ▸ | CES2 | O00748 | 4/20 | 0.44 |
| ▸ | CES1 | P23141 | 4/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2380962 | 0.81 | KDM4E (0.48) | PTGS2CES2CES1ESR1ALDH1A1 | |
| SCHEMBL603366 | 0.78 | PTGS2 (0.42) | PTGS2CES2CES1ESR1ALDH1A1 | |
| SCHEMBL29131554 | 0.78 | PTGS2 (0.49) | PTGS2CES2CES1ESR1ALDH1A1 | |
| SCHEMBL272292 | 0.78 | CES2 (0.51) | PTGS2CES2CES1ESR1ALDH1A1 | |
| SCHEMBL28273252 | 0.78 | PTGS2 (0.49) | PTGS2CES2CES1ESR1ALDH1A1 | |
| SCHEMBL7944718 | 0.77 | PTGS2 (0.55) | PTGS2CES2CES1ESR1ALDH1A1 | |
| SCHEMBL4822579 | 0.74 | PTGS2 (0.52) | PTGS2CES2CES1ESR1ALDH1A1 | |
| SCHEMBL27699487 | 0.74 | PTGS2 (0.52) | PTGS2CES2CES1ESR1ALDH1A1 | |
| SCHEMBL3685990 | 0.74 | PTGS2 (0.52) | PTGS2CES2CES1ESR1ALDH1A1 | |
| SCHEMBL113321 | 0.73 | CES2 (0.53) | PTGS2CES2CES1NAAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108884322-B | Addition one-liquid heat-curable heat-conductive silicone grease composition and method for producing cured product thereof | 信越化学工业株式会社 | 2021-08-24 | — | — | CN | disclosed |