Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 2/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | PRKDC | P78527 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.50 |
| ▸ | TYR | P14679 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30320420 | 1.00 | ERN1 (0.62) | ERN1HTTALDH1A1KDM4ETDP1 | |
| SCHEMBL4340842 | 0.87 | ERN1 (0.52) | ERN1HTTALDH1A1KDM4ETDP1 | |
| SCHEMBL31597603 | 0.86 | ERN1 (0.62) | ERN1HTTALDH1A1KDM4ETDP1 | |
| SCHEMBL1098465 | 0.86 | ERN1 (0.62) | ERN1HTTALDH1A1KDM4ETDP1 | |
| SCHEMBL12885860 | 0.85 | HTT (0.57) | ERN1HTTALDH1A1KDM4ETDP1 | |
| SCHEMBL12343265 | 0.85 | HTT (0.60) | ERN1HTTALDH1A1KDM4ETDP1 | |
| SCHEMBL3557471 | 0.85 | HTT (0.60) | ERN1HTTALDH1A1KDM4ETDP1 | |
| SCHEMBL5737354 | 0.84 | ABCB1 (0.50) | ERN1HTTALDH1A1KDM4ECYP3A4 | |
| SCHEMBL8329402 | 0.83 | ERN1 (0.57) | ERN1HTTALDH1A1KDM4ECYP3A4 | |
| SCHEMBL27787985 | 0.83 | ERN1 (0.53) | ERN1HTTALDH1A1KDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 273 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119242005-A | Production process for biodegradable plastic and application thereof | 河北雄安骅洋纸塑包装实业有限公司 | 2025-01-03 | — | — | CN | claimed |
| JP-2002523448-A | — | — | 2002-07-30 | — | — | JP | claimed |
| US-6410540-B1 | HEART AND KIDNEY DISEASES; ANTIINFLAMMATORY AGENTS | SCIOS, INC. | 2002-06-25 | — | — | US | claimed |
| EP-1107758-A2 | USE OF PIPERIDINES AND/OR PIPERAZINES AS INHIBITORS OF P38-ALPHA KINASE | SCIOS INC. (US) | 2001-06-20 | — | — | EP | claimed |
| WO-2000012074-A2 | USE OF PIPERIDINES AND/OR PIPERAZINES AS INHIBITORS OF P38-ALPHA KINASE | SCIOS INC. (US) | 2000-03-09 | — | — | WO | claimed |
| US-12630542-B2 | Compounds and their use as therapeutically active substances in the treatment and/or prevention of diseases involving the retinal pigment epithelium | ENDOGENA THERAPEUTICS, INC. (US) | 2026-05-19 | — | — | US | disclosed |
| US-12583822-B2 | Benzylamine derivative, preparation method therefor and use thereof | ACADEMY OF MILITARY MEDICAL SCIENCES (CN) | 2026-03-24 | — | — | US | disclosed |
| EP-4707264-A2 | COMPOUNDS AND THE USE THEREOF IN METATHESIS REACTIONS | Verbio SE (DE) | 2026-03-11 | — | — | EP | disclosed |
| EP-4122924-B1 | COMPOUNDS AND THE USE THEREOF IN METATHESIS REACTIONS | VERBIO SE (DE) | 2025-11-19 | — | — | EP | disclosed |
| EP-3590516-B1 | ANTITUMOR-EFFECT ENHANCER USING PYRAZOLO[3,4-D]PYRIMIDINE COMPOUND | TAIHO PHARMACEUTICAL CO LTD (JP) | 2025-09-03 | — | — | EP | disclosed |
| US-12195452-B2 | N-(4-(oxazol-5-yl)phenyl) chromane-3-carboxamide derivatives and related compounds as stimulators of the production of retinal precursor cells for the treatment of neuroretinal diseases | ENDOGENA THERAPEUTICS, INC. (US) | 2025-01-14 | — | — | US | disclosed |
| US-20250011330-A1 | Imidazo[1,2- a]pyrazine and Imidazo[1,2- a]pyridine Based Tyrosyl-DNA Phosphodiesterase I (TDP1) Inhibitors | LEIDOS BIOMEDICAL RESEARCH INC. | 2025-01-09 | — | — | US | disclosed |
| WO-2000025780-A1 | COMPOUNDS DERIVED FROM AN AMINE NUCLEUS THAT ARE INHIBITORS OF IMPDH ENZYME | BRISTOL-MYERS SQUIBB COMPANY (US) | 2000-05-11 | — | — | WO | disclosed |
| WO-2000026197-A1 | NOVEL INHIBITORS OF IMPDH ENZYME | BRISTOL-MYERS SQUIBB COMPANY (US) | 2000-05-11 | — | — | WO | disclosed |
| EP-0794951-B1 | PROCESSES AND INTERMEDIATES FOR PREPARING CIS (+) 3-[4,6-DIHYDROXYCHROMAN-3-YLMETHYL]-4-METHOXYANILINE | PFIZER (US) | 2000-04-12 | — | — | EP | disclosed |
| EP-0794951-A1 | PROCESSES AND INTERMEDIATES FOR PREPARING CIS(+)3- 4,-6-DIHYDROXYCHROMAN-3-YLMETHYL]-4-METHOXYANILINE | Pfizer Hospital Products Group, Inc. (US) | 1997-09-17 | — | — | EP | disclosed |
| US-5539128-A | Processes and intermediates for preparing cis(+)3-[4,6-dihydroxy chroman-3-ylmethyl]-4-methoxyaniline | PFIZER INC. (US) | 1996-07-23 | — | — | US | disclosed |
| WO-1996016955-A1 | PROCESSES AND INTERMEDIATES FOR PREPARING CIS(+)3-[4,-6-DIHYDROXYCHROMAN-3-YLMETHYL]-4-METHOXYANILINE | PFIZER INC. (US) | 1996-06-06 | — | — | WO | disclosed |
| US-5208341-A | Pressure sensitive copying; thermoreactive or electrochromic recording materials | BAYER AKTIENGESELLSCHAFT (DE) | 1993-05-04 | — | — | US | disclosed |
| EP-0480276-A2 | Carbonylaminostyrene derivatives as recording material | BAYER AG (DE) | 1992-04-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12630542-B2 | Compounds and their use as therapeutically active substances in the treatment and/or prevention of diseases involving the retinal pigment epithelium | ALDH1A2, NR2E3, GFRA1 | ERN1 2860/4885HTT 1525/4885ALDH1A1 375/4885 |
| US-12195452-B2 | N-(4-(oxazol-5-yl)phenyl) chromane-3-carboxamide derivatives and related compounds as stimulators of the production of retinal precursor cells for the treatment of neuroretinal diseases | NR2E3, GFRA2, ALDH1A2 | ERN1 2255/4885HTT 3177/4885ALDH1A1 1885/4885 |
| US-20250011330-A1 | Imidazo[1,2- a]pyrazine and Imidazo[1,2- a]pyridine Based Tyrosyl-DNA Phosphodiesterase I (TDP1) Inhibitors | TDP1, TDP2, TOP1 | ERN1 286/4885HTT 2185/4885ALDH1A1 769/4885 |
| US-12583822-B2 | Benzylamine derivative, preparation method therefor and use thereof | CD274, PDCD1, PDCD1LG2 | ERN1 4346/4885HTT 3633/4885ALDH1A1 612/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.