Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.42 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.42 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2246787 | 0.86 | ERN1 (0.62) | ERN1ALDH1A1MAPTHTTTTR | |
| SCHEMBL286441 | 0.83 | ERN1 (0.62) | ERN1ALDH1A1MAPTHTTPKM | |
| SCHEMBL27787985 | 0.83 | ERN1 (0.53) | ERN1ALDH1A1MAPTHTTTTR | |
| SCHEMBL30320420 | 0.83 | ERN1 (0.62) | ERN1ALDH1A1MAPTHTTPKM | |
| SCHEMBL8964120 | 0.81 | LMNA (0.56) | ERN1ALDH1A1MAPTKMT2AHPGD | |
| SCHEMBL3722677 | 0.79 | ERN1 (0.49) | ERN1ALDH1A1MAPTHTTTTR | |
| SCHEMBL1669597 | 0.79 | ALDH1A1 (0.50) | ERN1ALDH1A1MAPTHTTKMT2A | |
| SCHEMBL14384260 | 0.79 | ERN1 (0.49) | ERN1ALDH1A1MAPTHTTKMT2A | |
| SCHEMBL28077654 | 0.78 | KMT2A (0.59) | ERN1ALDH1A1MAPTHTTTTR | |
| SCHEMBL2652355 | 0.77 | ERN1 (0.69) | ERN1ALDH1A1MAPTHTTPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869787-A4 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 1999-03-24 | — | — | EP | disclosed |
| EP-0869787-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-10-14 | — | — | EP | disclosed |
| WO-1997024119-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-07-10 | — | — | WO | disclosed |