SCHEMBL28645178

SCHEMBL28645178

CCC(CO)(COC(=O)CCCCC(=O)O)[N+](=O)[O-]

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PAM P19021 2/20 0.37
TSHR P16473 5/20 0.35
AKR1B1 P15121 1/20 0.34
PPARG P37231 13/20 0.34
PPARA Q07869 8/20 0.34
TRPA1 O75762 1/20 0.34
FBP1 P09467 1/20 0.34
PPARD Q03181 6/20 0.33
HDAC11 Q96DB2 5/20 0.33
GPR84 Q9NQS5 4/20 0.33
ALDH1A1 P00352 2/20 0.33
TLR2 O60603 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
FABP4 P15090 2/20 0.33
PTPN1 P18031 2/20 0.33
SLC22A6 Q4U2R8 1/20 0.33
SLC22A8 Q8TCC7 1/20 0.33
MEN1 O00255 1/20 0.33
ESR1 P03372 1/20 0.33
ALOX15 P16050 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28635287 0.94 DGKA (0.37) PAMTSHRALDH1A1TDP1MEN1
Adipic Acid SCHEMBL29215200 0.85 AKR1B1 (0.43) TSHRAKR1B1PPARGPPARATRPA1
SCHEMBL28576093 0.79 TSHR (0.37) PAMTSHRAKR1B1PPARGPPARA
SCHEMBL1104240 0.75 PAM (0.43) PAMTSHRAKR1B1PPARGPPARA
SCHEMBL6516909 0.73 NAAA (0.34) ALDH1A1KMT2A
SCHEMBL15798231 0.73 THRB (0.39) TSHRALDH1A1
Propionic Acid SCHEMBL6895209 0.72 FFAR3 (0.42) ALDH1A1TDP1MEN1KMT2A
SCHEMBL16248491 0.72 TSHR (0.46) PAMTSHRAKR1B1PPARGPPARA
SCHEMBL28570150 0.72 DGKA (0.35) PAMTSHRALDH1A1TDP1MEN1
SCHEMBL12192458 0.72 TSHR (0.44) PAMTSHRAKR1B1PPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110452366-B Poly (2-ethyl-2-nitropropanediol adipate), preparation method and application thereof 西安近代化学研究所 2021-10-01 CN disclosed
CN-110452366-B Poly (2-ethyl-2-nitropropanediol adipate), preparation method and application thereof 西安近代化学研究所 2021-10-01 CN disclosed