Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.47 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.43 |
| ▸ | FURIN | P09958 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8204708 | 0.84 | ALDH1A1 (0.75) | ALDH1A1LMNAMAPTHPGDSMN1; SMN2 | |
| SCHEMBL5090074 | 0.84 | ALDH1A1 (0.75) | ALDH1A1LMNAMAPTHPGDSMN1; SMN2 | |
| SCHEMBL20874022 | 0.81 | LMNA (0.49) | ALDH1A1LMNAMAPTPARP10KMT2A | |
| SCHEMBL7777481 | 0.81 | THRB (0.58) | ALDH1A1LMNAMAPTHPGDSMN1; SMN2 | |
| SCHEMBL13547835 | 0.80 | ALDH1A1 (0.57) | ALDH1A1LMNAMAPTHPGDSMN1; SMN2 | |
| SCHEMBL8551794 | 0.80 | ALDH1A1 (0.69) | ALDH1A1LMNAMAPTHPGDSMN1; SMN2 | |
| SCHEMBL13361241 | 0.80 | ALDH1A1 (0.53) | ALDH1A1LMNAMAPTHPGDSMN1; SMN2 | |
| SCHEMBL2558719 | 0.79 | ALDH1A1 (0.51) | ALDH1A1LMNAMAPTHPGDSMN1; SMN2 | |
| SCHEMBL28911876 | 0.79 | LMNA (0.46) | LMNAPARP10TMPRSS2FURINPRSS1 | |
| SCHEMBL22005162 | 0.79 | ALDH1A1 (0.64) | ALDH1A1LMNAMAPTHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113454086-A | Imidazo [2,1-F ] [1,2,4] triazin-4-amine derivatives as TLR7 agonists | 百济神州有限公司 | 2021-09-28 | — | — | CN | disclosed |