Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 3/20 | 0.57 |
| ▸ | CASP1 | P29466 | 9/20 | 0.53 |
| ▸ | CTSL | P07711 | 1/20 | 0.53 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.50 |
| ▸ | PLG | P00747 | 1/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.50 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.50 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.50 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.50 |
| ▸ | LGMN | Q99538 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17841948 | 0.99 | CTSK (0.56) | CTSKCASP1CTSLPSMB8PSMB9 | |
| SCHEMBL14433707 | 0.90 | MME (0.59) | CTSKCASP1PSMB8PSMB9PSMB5 | |
| SCHEMBL7155003 | 0.90 | MME (0.59) | CTSKCASP1PSMB8PSMB9PSMB5 | |
| SCHEMBL4430771 | 0.90 | MME (0.59) | CTSKCASP1PSMB8PSMB9PSMB5 | |
| SCHEMBL29453232 | 0.89 | MME (0.58) | CTSKCASP1PSMB8PSMB9PSMB5 | |
| SCHEMBL8553630 | 0.88 | CASP1 (0.64) | CASP1CTSL | |
| SCHEMBL6159279 | 0.88 | CASP1 (0.64) | CASP1CTSL | |
| SCHEMBL10868042 | 0.87 | CAPN1 (0.58) | CTSKCASP1 | |
| SCHEMBL19067195 | 0.86 | CASP1 (0.57) | CTSKCASP1 | |
| SCHEMBL11697381 | 0.85 | CASP1 (0.56) | CTSKCASP1CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107635586-B | Antibody-drug conjugates (ADC) of KSP inhibitors with aglycosylated anti-TWEAKR antibodies | 拜耳医药股份有限公司 | 2021-09-24 | — | — | CN | disclosed |