Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.49 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.49 |
| ▸ | TGM2 | P21980 | 1/20 | 0.48 |
| ▸ | CPB1 | P15086 | 1/20 | 0.46 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.45 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.45 |
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13622431 | 1.00 | HTT (0.50) | HTTKEAP1NFE2L2TGM2CPB1 | |
| SCHEMBL989685 | 0.92 | TGM2 (0.55) | HTTKEAP1NFE2L2TGM2LMNA | |
| SCHEMBL13622435 | 0.91 | LMNA (0.49) | HTTKEAP1NFE2L2TGM2LMNA | |
| SCHEMBL8039590 | 0.89 | HTT (0.52) | HTTKEAP1NFE2L2TGM2LMNA | |
| SCHEMBL14628582 | 0.88 | HTT (0.64) | HTTKEAP1NFE2L2TGM2CPB1 | |
| SCHEMBL14598314 | 0.88 | HTT (0.64) | HTTKEAP1NFE2L2TGM2CPB1 | |
| SCHEMBL7318682 | 0.88 | HTT (0.64) | HTTKEAP1NFE2L2TGM2CPB1 | |
| SCHEMBL7319378 | 0.87 | HTT (0.62) | HTTKEAP1NFE2L2TGM2LMNA | |
| SCHEMBL7858088 | 0.87 | CCR6 (0.50) | HTTKEAP1NFE2L2TGM2LMNA | |
| SCHEMBL8029846 | 0.87 | HTT (0.62) | HTTKEAP1NFE2L2TGM2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113423877-A | Mutant tRNAs for codon expansion | 中外制药株式会社 | 2021-09-21 | — | — | CN | disclosed |