Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOX | P28300 | 15/20 | 0.55 |
| ▸ | LOXL2 | Q9Y4K0 | 6/20 | 0.55 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28651581 | 0.86 | LOX (0.53) | LOXLOXL2MAOA | |
| SCHEMBL28643887 | 0.84 | LOX (0.59) | LOXLOXL2LOXL3KCNH2AOC3 | |
| SCHEMBL28643855 | 0.82 | LOX (0.53) | LOXLOXL2LOXL3KCNH2AOC3 | |
| SCHEMBL28644262 | 0.82 | PKM (0.59) | LOXGAA | |
| Hydrochloric Acid SCHEMBL28644204 | 0.81 | LOX (0.55) | LOXLOXL2LOXL3KCNH2AOC3 | |
| SCHEMBL28644288 | 0.79 | LOX (0.63) | LOXLOXL2LOXL3KCNH2AOC3 | |
| SCHEMBL28657427 | 0.79 | LOX (0.59) | LOXLOXL2GAA | |
| SCHEMBL28657105 | 0.78 | LOXL2 (0.64) | LOXLOXL2LOXL3KCNH2AOC3 | |
| SCHEMBL28657417 | 0.77 | LOXL2 (0.65) | LOXLOXL2LOXL3KCNH2AOC3 | |
| SCHEMBL28646901 | 0.76 | LOXL2 (0.58) | LOXLOXL2KCNH2AOC3MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109311839-B | Methylamine derivatives as lysyl oxidase inhibitors for the treatment of cancer | 癌症研究协会皇家癌症医院 | 2021-11-02 | — | — | CN | disclosed |