Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 8/20 | 0.58 |
| ▸ | LOX | P28300 | 4/20 | 0.58 |
| ▸ | MAOA | P21397 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | C1S | P09871 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | PKLR | P30613 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28651581 | 0.83 | LOX (0.53) | LOXL2LOXMAOAMEN1KMT2A | |
| SCHEMBL28641783 | 0.79 | LOXL2 (0.58) | LOXL2LOXMAOAL3MBTL1KCNH2 | |
| SCHEMBL28643887 | 0.78 | LOX (0.59) | LOXL2LOXKCNH2AOC3LMNA | |
| Hydrochloric Acid SCHEMBL28644204 | 0.78 | LOX (0.55) | LOXL2LOXMAOAKCNH2AOC3 | |
| SCHEMBL1952494 | 0.77 | LMNA (0.68) | LOXL2LOXMAOAL3MBTL1LMNA | |
| SCHEMBL28645837 | 0.76 | LOX (0.55) | LOXL2LOXMAOAKCNH2AOC3 | |
| SCHEMBL28644262 | 0.76 | PKM (0.59) | LOXPKM | |
| SCHEMBL28646852 | 0.75 | LOX (0.66) | LOXL2LOXMAOAKCNH2AOC3 | |
| SCHEMBL19259736 | 0.75 | LOXL2 (0.59) | LOXL2LOXMAOAL3MBTL1KCNH2 | |
| SCHEMBL19259969 | 0.73 | LOX (1.00) | LOXL2LOXMAOAKCNH2AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109311839-B | Methylamine derivatives as lysyl oxidase inhibitors for the treatment of cancer | 癌症研究协会皇家癌症医院 | 2021-11-02 | — | — | CN | disclosed |