SCHEMBL28645941

SCHEMBL28645941

[SiH3]OC(CCc1ccccc1)(Oc1ccccc1)Oc1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.36
ALDH1A1 P00352 1/20 0.35
HPGD P15428 1/20 0.35
ALOX15 P16050 1/20 0.35
ALOX12 P18054 1/20 0.35
CASP1 P29466 1/20 0.35
HSD17B10 Q99714 1/20 0.35
DRD2 P14416 1/20 0.35
DRD4 P21917 1/20 0.35
DRD3 P35462 1/20 0.35
TDP1 Q9NUW8 2/20 0.34
CYP2A6 P11509 1/20 0.34
HTR2A P28223 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
TAAR1 Q96RJ0 1/20 0.34
LOXL2 Q9Y4K0 1/20 0.34
PPARG P37231 2/20 0.33
IDO1 P14902 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28927876 0.79 ALDH1A1 (0.37) ALDH1A1HPGDALOX15ALOX12CASP1
SCHEMBL29151729 0.76 LTA4H (0.38)
SCHEMBL5027543 0.73 KCNA3 (0.41) ALDH1A1ALOX15DRD2DRD4DRD3
SCHEMBL9446218 0.73 TAAR1 (0.42) GAAALDH1A1HPGDALOX15ALOX12
SCHEMBL3581753 0.73 SMN1; SMN2 (0.41) GAAALDH1A1HPGDALOX15ALOX12
SCHEMBL10554265 0.71 SLC6A2 (0.43) GAASMN1; SMN2TAAR1PPARGIDO1
SCHEMBL964291 0.71 ALDH1A1 (0.39) GAAALDH1A1HPGDALOX15ALOX12
SCHEMBL28049304 0.70 PPARG (0.39) GAAALDH1A1HPGDALOX15ALOX12
SCHEMBL28647675 0.70 ALDH1A1 (0.37) ALDH1A1ALOX12SMN1; SMN2NPC1RAB9A
SCHEMBL18585417 0.70 LTA4H (0.36) ALDH1A1ALOX15TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109715680-B Process for preparing high cis-1, 4-polydienes with lanthanide-based catalyst compositions 株式会社普利司通 2021-10-19 CN disclosed