SCHEMBL28645971

SCHEMBL28645971

Cc1cccc(NNC2CCCCC2)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.57
RAB9A P51151 3/20 0.57
SMN1; SMN2 Q16637 2/20 0.55
HPGD P15428 1/20 0.55
ALOX12 P18054 1/20 0.55
GAA P10253 3/20 0.51
NPSR1 Q6W5P4 2/20 0.50
POLB P06746 1/20 0.48
MAPT P10636 3/20 0.46
HTT P42858 2/20 0.46
LMNA P02545 1/20 0.46
XBP1 P17861 1/20 0.46
ALDH1A1 P00352 2/20 0.45
KDM4E B2RXH2 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
CYP1A2 P05177 1/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2D6 P10635 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23441678 0.97 RAB9A (0.54) NPC1RAB9ASMN1; SMN2HPGDALOX12
SCHEMBL7299077 0.82 NPC1 (0.60) NPC1RAB9ASMN1; SMN2HPGDALOX12
SCHEMBL11526598 0.80 SMN1; SMN2 (0.59) NPC1RAB9ASMN1; SMN2HPGDALOX12
SCHEMBL5550812 0.79 LMNA (0.62) NPC1RAB9AHPGDALOX12GAA
SCHEMBL20892706 0.79 SMN1; SMN2 (0.52) RAB9ASMN1; SMN2HPGDGAAPOLB
SCHEMBL20926000 0.79 SMN1; SMN2 (0.52) RAB9ASMN1; SMN2HPGDGAAPOLB
SCHEMBL22792525 0.79 SMN1; SMN2 (0.52) RAB9ASMN1; SMN2HPGDGAAPOLB
SCHEMBL22732504 0.79 SMN1; SMN2 (0.52) RAB9ASMN1; SMN2HPGDGAAPOLB
SCHEMBL3091778 0.79 SMN1; SMN2 (0.52) RAB9ASMN1; SMN2HPGDGAAPOLB
SCHEMBL24949035 0.79 SMN1; SMN2 (0.52) RAB9ASMN1; SMN2HPGDGAAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109020827-B Method for synthesizing m-dialkylaminophenol 浙江山峪集团股份有限公司 2021-04-27 CN disclosed