Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 12/20 | 0.41 |
| ▸ | PREP | P48147 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.37 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28647324 | 0.83 | IDO1 (0.42) | IDO1CYP3A4 | |
| SCHEMBL23699089 | 0.79 | IDO1 (0.44) | MAPTTP53POLBIDO1PREP | |
| SCHEMBL21385177 | 0.74 | GFER (0.48) | MAPTTP53POLBIDO1PREP | |
| SCHEMBL30747808 | 0.73 | TSHR (0.58) | MAPTPOLBMEN1GAAHPGD | |
| SCHEMBL22270531 | 0.72 | IDO1 (0.48) | IDO1CYP3A4CYP2C9CHRNA1CYP2C8 | |
| SCHEMBL21381373 | 0.72 | GFER (0.47) | MAPTTP53POLBIDO1PREP | |
| SCHEMBL24089856 | 0.72 | IDO1 (0.55) | IDO1CYP3A4 | |
| SCHEMBL28656748 | 0.71 | IDO1 (0.62) | IDO1CYP3A4 | |
| SCHEMBL23707465 | 0.71 | NOS2 (0.43) | MAPTTP53POLBIDO1MEN1 | |
| SCHEMBL17729242 | 0.71 | CHRM4 (0.48) | MAPTTP53POLBIDO1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109575022-B | Compound and application thereof | 成都海博锐药业有限公司 | 2021-09-21 | — | — | CN | disclosed |