Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 11/20 | 0.34 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28642826 | 1.00 | RORC (0.34) | RORCDRD2ACACBCDK9GPR119 | |
| SCHEMBL28640862 | 0.88 | CKS1B (0.43) | RORCDRD2ACACB | |
| SCHEMBL28640864 | 0.88 | CKS1B (0.43) | RORCDRD2ACACB | |
| SCHEMBL28647151 | 0.84 | DRD2 (0.38) | RORCDRD2ACACBCDK9GPR119 | |
| SCHEMBL28656473 | 0.82 | CHRM3 (0.31) | — | |
| SCHEMBL28656471 | 0.82 | CHRM3 (0.31) | — | |
| SCHEMBL28642831 | 0.80 | ACACB (0.35) | RORCDRD2ACACB | |
| SCHEMBL28642843 | 0.78 | GPR119 (0.35) | RORCDRD2ACACBCDK9GPR119 | |
| SCHEMBL28642845 | 0.78 | GPR119 (0.35) | RORCDRD2ACACBCDK9GPR119 | |
| SCHEMBL28659971 | 0.77 | CKS1B (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113527298-A | Macrocyclic lactam derivative, preparation method and application thereof | 浙江海正药业股份有限公司 | 2021-10-22 | — | — | CN | disclosed |