SCHEMBL2864864

SCHEMBL2864864

Cc1cc(O)c(C2CCCCC2)cc1C1(c2cc(C3CCCCC3)c(O)cc2C)c2ccccc2-c2ccccc21

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.44
ESR2 Q92731 1/20 0.44
PDK2 Q15119 6/20 0.40
NUDT1 P36639 1/20 0.36
BACE1 P56817 1/20 0.36
HSP90AA1 P07900 1/20 0.36
PTGS2 P35354 1/20 0.35
LMNA P02545 4/20 0.34
MAPT P10636 4/20 0.34
NPSR1 Q6W5P4 2/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
TDP1 Q9NUW8 2/20 0.34
TP53 P04637 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2D6 P10635 1/20 0.34
CYP2C9 P11712 1/20 0.34
ALOX15 P16050 1/20 0.34
CYP2C19 P33261 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18948598 0.81 NUDT1 (0.42) PDK2NUDT1BACE1HSP90AA1PTGS2
SCHEMBL16429483 0.78 ESR1 (0.34) ESR1ESR2PDK2
SCHEMBL12339874 0.78 PDK2 (0.38) ESR1ESR2PDK2NUDT1BACE1
SCHEMBL29445693 0.78 ESR1 (0.54) ESR1ESR2PDK2NUDT1BACE1
SCHEMBL382817 0.78 ESR1 (0.54) ESR1ESR2PDK2NUDT1BACE1
SCHEMBL20590527 0.77 ESR1 (0.59) ESR1ESR2PDK2LMNAMAPT
SCHEMBL25280688 0.76 PDK2 (0.43) ESR1ESR2PDK2LMNAMAPT
SCHEMBL278203 0.76 ESR1 (0.62) ESR1ESR2PDK2LMNAMAPT
Orthocresol SCHEMBL15511894 0.74 NUDT1 (0.39) NUDT1BACE1HSP90AA1PTGS2LMNA
SCHEMBL8512038 0.74 NUDT1 (0.36) NUDT1BACE1HSP90AA1MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9676956-B2 (Meth)acrylic resin composition, film, polarizing plate protective film, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2017-06-13 US disclosed
US-9676956-B2 (Meth)acrylic resin composition, film, polarizing plate protective film, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2017-06-13 US disclosed
US-20160376463-A1 (METH)ACRYLIC RESIN COMPOSITION, FILM, POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2016-12-29 US disclosed
US-8057869-B2 Plastic film, gas barrier film, and image display device using the same FUJIFILM CORPORATION (JP) 2011-11-15 US disclosed
US-8057869-B2 Plastic film, gas barrier film, and image display device using the same FUJIFILM CORPORATION (JP) 2011-11-15 US disclosed
US-7713449-B2 Polymer electrolytic material, polymer electrolytic part, membrane electrode assembly, and polymer electrolyte fuel cell TORAY INDUSTRIES, INC. (JP) 2010-05-11 US disclosed
US-20060180796-A1 Polymer electrolyte material, polymer electrolyte part, membrane electrode composite and polymer electrolyte type fuel cell TORAY INDUSTRIES, INC. (JP) 2006-08-17 US disclosed
CN-1757130-A Polymer electrolyte material, polymer electrolyte part, film electrode composite element and polymer electrolyte fuel cells TORAY INDUSTRIES (JP) 2006-04-05 CN disclosed
EP-1619735-A1 POLYMER ELECTROLYTE MATERIAL, POLYMER ELECTROLYTE PART, MEMBRANE ELECTRODE COMPOSITE AND POLYMER ELECTROLYTE TYPE FUEL CELL TORAY INDUSTRIES, INC. (JP) 2006-01-25 EP disclosed
US-6841628-B2 Resin composition, adhesives prepared therewith for bonding circuit members, and circuit boards HITACHI CHEMICAL CO., LTD. (JP) 2005-01-11 US disclosed
US-20030027942-A1 Resin composition , adhesive prepared therewith for bonding circuit members,and circuit boards HITACHI CHEMICAL CO., LTD. (JP) 2003-02-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160376463-A1 (METH)ACRYLIC RESIN COMPOSITION, FILM, POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE METTL14, REV1, DRD2 ESR1 1484/4885ESR2 2146/4885PDK2 4691/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.