Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | AR | P10275 | 7/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30756603 | 0.80 | RAB9A (0.51) | RAB9ASMN1; SMN2ARNPC1LMNA | |
| SCHEMBL3550824 | 0.79 | L3MBTL1 (0.47) | RAB9ASMN1; SMN2ARNPC1LMNA | |
| SCHEMBL1168974 | 0.79 | ALDH1A1 (0.53) | RAB9ASMN1; SMN2ARNPC1LMNA | |
| SCHEMBL28657476 | 0.77 | AR (0.54) | RAB9ASMN1; SMN2ARNPC1LMNA | |
| SCHEMBL3435755 | 0.76 | OGA (0.45) | SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL2698786 | 0.75 | NPC1 (0.60) | RAB9ASMN1; SMN2ARNPC1LMNA | |
| SCHEMBL3159092 | 0.75 | CHRNB2 (0.42) | RAB9ASMN1; SMN2ARNPC1LMNA | |
| SCHEMBL1434351 | 0.72 | RAB9A (0.54) | RAB9ASMN1; SMN2NPC1LMNAMAPT | |
| SCHEMBL15333499 | 0.71 | HRH3 (0.44) | RAB9ASMN1; SMN2ARLMNAMAPT | |
| SCHEMBL21192403 | 0.71 | SMN1; SMN2 (0.51) | RAB9ASMN1; SMN2NPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106478564-B | Cathepsin K inhibitors and uses thereof | 广东东阳光药业有限公司 | 2021-11-12 | — | — | CN | disclosed |