Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBK1 | Q9UHD2 | 8/20 | 0.43 |
| ▸ | CREBBP | Q92793 | 5/20 | 0.40 |
| ▸ | BRD4 | O60885 | 3/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28649787 | 0.83 | CREBBP (0.41) | CREBBPBRD4 | |
| SCHEMBL30395478 | 0.82 | CREBBP (0.41) | CREBBPBRD4 | |
| SCHEMBL25198716 | 0.82 | CREBBP (0.41) | CREBBPBRD4 | |
| SCHEMBL31692747 | 0.80 | GPR119 (0.42) | GPR119 | |
| SCHEMBL31496122 | 0.78 | CREBBP (0.70) | CREBBPBRD4 | |
| SCHEMBL30394981 | 0.76 | KDM4E (0.44) | GPR119 | |
| SCHEMBL23930186 | 0.76 | KDM4E (0.44) | GPR119 | |
| SCHEMBL25193494 | 0.73 | PDK4 (0.47) | — | |
| SCHEMBL30395928 | 0.73 | PDK4 (0.47) | — | |
| SCHEMBL31496201 | 0.73 | MGLL (0.40) | TBK1CREBBPBRD4GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250136578-A1 | BIFUNCTIONAL ANDROGEN RECEPTOR COMPOUNDS | KOLM THERAPEUTICS INC. | 2025-05-01 | — | — | US | disclosed |
| WO-2025081092-A1 | BIFUNCTIONAL ANDROGEN RECEPTOR COMPOUNDS | KOLM THERAPEUTICS INC. (US) | 2025-04-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250136578-A1 | BIFUNCTIONAL ANDROGEN RECEPTOR COMPOUNDS | AR, SHBG, FSHR | TBK1 1620/4885CREBBP 2932/4885BRD4 674/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.