SCHEMBL2865037

SCHEMBL2865037

CCOC(=O)c1cc(O)cc(OC(=O)CCC(=O)O)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 0.59
CA1 P00915 3/20 0.59
CA2 P00918 3/20 0.59
CA7 P43166 3/20 0.59
CA9 Q16790 3/20 0.59
CA14 Q9ULX7 3/20 0.59
ESR1 P03372 1/20 0.44
ESR2 Q92731 1/20 0.44
NR1H2 P55055 1/20 0.43
NR1H3 Q13133 1/20 0.43
HTT P42858 1/20 0.42
F2 P00734 2/20 0.40
F10 P00742 2/20 0.40
CYP3A4 P08684 2/20 0.40
MEN1 O00255 1/20 0.40
SLC22A2 O15244 1/20 0.40
TMPRSS2 O15393 1/20 0.40
PLG P00747 1/20 0.40
F12 P00748 1/20 0.40
PLAU P00749 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2875378 0.92 CA12 (0.56) CA12CA1CA2CA7CA9
SCHEMBL14374036 0.77 CA12 (0.73) CA12CA1CA2CA7CA9
SCHEMBL5415007 0.77 CA12 (0.73) CA12CA1CA2CA7CA9
SCHEMBL475700 0.77 CA12 (0.92) CA12CA1CA2CA7CA9
SCHEMBL39026 0.77 CA12 (1.00) CA12CA1CA2CA7CA9
SCHEMBL16326875 0.76 PLA2G2A (0.47) CA12CA1CA2CA7CA9
SCHEMBL57016 0.74 CA12 (0.79) CA12CA1CA2CA7CA9
SCHEMBL8655756 0.73 KMT2A (0.48) CA12CA1CA2CA7CA9
SCHEMBL19809534 0.72 CA12 (0.59) CA12CA1CA2CA7CA9
SCHEMBL2257945 0.72 CA12 (0.81) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10383841-B2 Antimicrobial and antiinflammatory composition DENOVASTELLA AB (SE) 2019-08-20 US disclosed
EP-2150119-B1 DIHYDROXYBENZOATE POLYMERS AND USES THEREOF TYRX INC (US) 2018-04-11 EP disclosed
US-9491966-B2 Dihydroxybenzoate polymers and uses thereof TYRX, INC. (US) 2016-11-15 US disclosed
EP-1898893-B1 ANTIMICROBIAL COMPOSITION DENOVASTELLA AB (SE) 2014-09-24 EP disclosed
US-20130245112-A1 ANTIMICROBIAL AND ANTIINFLAMMATORY COMPOSITION DENOVASTELLA AB (SE) 2013-09-19 US disclosed
US-20100331401-A1 ANTIMICROBIAL AND ANTIINFLAMMATORY COMPOSITION DENOVASTELLA AB (SE) 2010-12-30 US disclosed
US-20100129417-A1 Dihydroxybenzoate Polymers and Uses Thereof MEDTRONIC, INC. 2010-05-27 US disclosed
EP-2150119-A1 DIHYDROXYBENZOATE POLYMERS AND USES THEREOF TYRX PHARMA INC. (US) 2010-02-10 EP disclosed
WO-2008137807-A1 DIHYDROXYBENZOATE POLYMERS AND USES THEREOF TYRX PHARMA, INC. (US) 2008-11-13 WO disclosed
US-20080249164-A1 Antimicrobial and Antinflammatory Composition DENOVASTELLA AB (SE) 2008-10-09 US disclosed
EP-1898893-A1 ANTIMICROBIAL AND ANTIINFLAMMATORY COMPOSITION Denovastella AB (SE) 2008-03-19 EP disclosed
WO-2007004952-A1 ANTIMICROBIAL AND ANTIINFLAMMATORY COMPOSITION DENOVASTELLA AB (SE) 2007-01-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100129417-A1 Dihydroxybenzoate Polymers and Uses Thereof DDT, QDPR, HPD CA12 2991/4885CA1 3801/4885CA2 3493/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.