Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.56 |
| ▸ | CA1 | P00915 | 3/20 | 0.56 |
| ▸ | CA2 | P00918 | 3/20 | 0.56 |
| ▸ | CA7 | P43166 | 3/20 | 0.56 |
| ▸ | CA9 | Q16790 | 3/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.56 |
| ▸ | F2 | P00734 | 2/20 | 0.44 |
| ▸ | F10 | P00742 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.44 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.44 |
| ▸ | PLG | P00747 | 1/20 | 0.44 |
| ▸ | F12 | P00748 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | PLAT | P00750 | 1/20 | 0.44 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | HPN | P05981 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2865037 | 0.92 | CA12 (0.59) | CA12CA1CA2CA7CA9 | |
| SCHEMBL17203211 | 0.81 | VCAM1 (0.46) | KMT2AMAPTEGFRVCAM1HTT | |
| SCHEMBL2849301 | 0.80 | VCAM1 (0.44) | MEN1KMT2AL3MBTL1VCAM1ALDH1A1 | |
| Alcohol SCHEMBL10867294 | 0.77 | VCAM1 (0.46) | MEN1KMT2AESR1TDP1VCAM1 | |
| SCHEMBL14374036 | 0.75 | CA12 (0.73) | CA12CA1CA2CA7CA9 | |
| SCHEMBL5415007 | 0.75 | CA12 (0.73) | CA12CA1CA2CA7CA9 | |
| SCHEMBL8651557 | 0.74 | KMT2A (0.44) | CA12CA1CA2CA7CA9 | |
| SCHEMBL39026 | 0.74 | CA12 (1.00) | CA12CA1CA2CA7CA9 | |
| SCHEMBL475700 | 0.74 | CA12 (0.92) | CA12CA1CA2CA7CA9 | |
| SCHEMBL10599097 | 0.74 | KMT2A (0.69) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2150119-B1 | DIHYDROXYBENZOATE POLYMERS AND USES THEREOF | TYRX INC (US) | 2018-04-11 | — | — | EP | disclosed |
| US-9491966-B2 | Dihydroxybenzoate polymers and uses thereof | TYRX, INC. (US) | 2016-11-15 | — | — | US | disclosed |
| US-20100129417-A1 | Dihydroxybenzoate Polymers and Uses Thereof | MEDTRONIC, INC. | 2010-05-27 | — | — | US | disclosed |
| EP-2150119-A1 | DIHYDROXYBENZOATE POLYMERS AND USES THEREOF | TYRX PHARMA INC. (US) | 2010-02-10 | — | — | EP | disclosed |
| WO-2008137807-A1 | DIHYDROXYBENZOATE POLYMERS AND USES THEREOF | TYRX PHARMA, INC. (US) | 2008-11-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100129417-A1 | Dihydroxybenzoate Polymers and Uses Thereof | DDT, QDPR, HPD | CA12 2991/4885CA1 3801/4885CA2 3493/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.