Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | GRIN1 | Q05586 | 5/20 | 0.55 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.55 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | HTR1D | P28221 | 1/20 | 0.50 |
| ▸ | HTR1B | P28222 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.49 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.49 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.49 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.49 |
| ▸ | PYGL | P06737 | 1/20 | 0.47 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.46 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28668119 | 0.90 | ALDH1A1 (0.59) | GBA1ALDH1A1GRIN1GRIN2BHTR1A | |
| SCHEMBL19555741 | 0.86 | ALDH1A1 (0.59) | GBA1ALDH1A1GRIN1GRIN2BMEN1 | |
| SCHEMBL28670635 | 0.85 | ITGB3 (0.59) | GBA1ALDH1A1GRIN1GRIN2BMEN1 | |
| SCHEMBL28668110 | 0.85 | ALDH1A1 (0.60) | GBA1ALDH1A1GRIN1GRIN2BMEN1 | |
| SCHEMBL5998019 | 0.85 | MEN1 (0.60) | MEN1HTTKMT2AKDM4EADAMTS5 | |
| SCHEMBL28668616 | 0.83 | ALDH1A1 (0.55) | GBA1ALDH1A1GRIN1GRIN2BMEN1 | |
| SCHEMBL28654035 | 0.83 | ALDH1A1 (0.77) | GBA1ALDH1A1GRIN1GRIN2BMEN1 | |
| SCHEMBL28655102 | 0.82 | GRIN1 (0.65) | GBA1ALDH1A1GRIN1GRIN2BMEN1 | |
| SCHEMBL28655075 | 0.82 | ALDH1A1 (0.59) | GBA1ALDH1A1GRIN1GRIN2BMEN1 | |
| SCHEMBL25811671 | 0.82 | ALDH1A1 (0.63) | GBA1ALDH1A1GRIN1GRIN2BMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113692276-A | NURR1 receptor modulators | 加利福尼亚大学董事会 | 2021-11-23 | — | — | CN | disclosed |