Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.77 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | GRIN1 | Q05586 | 5/20 | 0.59 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | GBA1 | P04062 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | PPARG | P37231 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.54 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.54 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.54 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.50 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28655075 | 0.87 | ALDH1A1 (0.59) | ALDH1A1RAB9AGRIN1GRIN2BGBA1 | |
| SCHEMBL28668119 | 0.87 | ALDH1A1 (0.59) | ALDH1A1GRIN1GRIN2BGBA1HTT | |
| SCHEMBL25811671 | 0.87 | ALDH1A1 (0.63) | ALDH1A1RAB9AGRIN1GRIN2BGBA1 | |
| SCHEMBL28668110 | 0.84 | ALDH1A1 (0.60) | ALDH1A1GRIN1GRIN2BGBA1HTT | |
| SCHEMBL28650418 | 0.83 | GBA1 (0.56) | ALDH1A1GRIN1GRIN2BGBA1HTT | |
| SCHEMBL19555741 | 0.83 | ALDH1A1 (0.59) | ALDH1A1GRIN1GRIN2BGBA1HTT | |
| SCHEMBL10090423 | 0.83 | RAB9A (0.70) | ALDH1A1RAB9ASMN1; SMN2HTTMEN1 | |
| SCHEMBL28668976 | 0.82 | GRIN1 (0.60) | ALDH1A1GRIN1GRIN2BSMN1; SMN2GBA1 | |
| SCHEMBL28668101 | 0.82 | GRIN1 (0.57) | ALDH1A1GRIN1GRIN2BGBA1HTT | |
| SCHEMBL28650889 | 0.82 | PTPN1 (0.61) | ALDH1A1GRIN1GRIN2BHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113692276-A | NURR1 receptor modulators | 加利福尼亚大学董事会 | 2021-11-23 | — | — | CN | disclosed |