Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CA5A | P35218 | 3/20 | 0.42 |
| ▸ | CA9 | Q16790 | 3/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA3 | P07451 | 2/20 | 0.42 |
| ▸ | CA4 | P22748 | 2/20 | 0.42 |
| ▸ | CA6 | P23280 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 2/20 | 0.42 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23319834 | 0.85 | CA2 (0.58) | CA2LMNAMEN1KMT2ACA1 | |
| SCHEMBL2825786 | 0.82 | ALDH1A1 (0.62) | CA2LMNAKDM4EMEN1KMT2A | |
| SCHEMBL4844487 | 0.81 | KMT2A (0.50) | CA2LMNAKDM4EMEN1KMT2A | |
| SCHEMBL12225751 | 0.81 | HSD17B10 (0.54) | CA2LMNAKDM4EMEN1KMT2A | |
| SCHEMBL29910041 | 0.80 | LMNA (0.51) | CA2LMNACA1CA5ACA9 | |
| SCHEMBL23320079 | 0.80 | LMNA (0.51) | CA2LMNACA1CA5ACA9 | |
| SCHEMBL19119211 | 0.79 | POLB (0.59) | LMNAKDM4EMEN1KMT2APOLB | |
| SCHEMBL13543494 | 0.78 | CYP3A4 (0.52) | CA2LMNAKDM4EMEN1KMT2A | |
| SCHEMBL30602792 | 0.78 | LMNA (0.45) | CA2LMNAKDM4EMEN1KMT2A | |
| SCHEMBL29602365 | 0.78 | CYP3A4 (0.52) | CA2LMNAKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113613721-A | NLRP modulators | 诺华股份有限公司 | 2021-11-05 | — | — | CN | disclosed |