SCHEMBL4844487

SCHEMBL4844487

CNS(=O)(=O)c1ccc(N)c(C(=O)O)c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.50
KDM4E B2RXH2 3/20 0.50
ALDH1A1 P00352 1/20 0.50
CDC25B P30305 1/20 0.50
CASP6 P55212 1/20 0.50
RCE1 Q9Y256 1/20 0.50
GFER P55789 1/20 0.50
RXFP1 Q9HBX9 1/20 0.50
POLB P06746 3/20 0.49
MEN1 O00255 3/20 0.49
USP2 O75604 1/20 0.49
MAPT P10636 1/20 0.49
THRB P10828 1/20 0.49
PKM P14618 1/20 0.49
APEX1 P27695 1/20 0.49
RECQL P46063 1/20 0.49
BLM P54132 1/20 0.49
MCL1 Q07820 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
GLA P06280 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23319841 0.84 ALDH1A1 (0.58) KMT2AKDM4EALDH1A1MEN1MAPT
SCHEMBL10979724 0.83 ALDH1A1 (0.49) KMT2AKDM4EALDH1A1CDC25BCASP6
SCHEMBL10984175 0.83 NPSR1 (0.48) KMT2AKDM4EALDH1A1CDC25BCASP6
SCHEMBL29505008 0.82 LMNA (0.44) KMT2AKDM4EALDH1A1MEN1MAPT
SCHEMBL22719745 0.82 LMNA (0.44) KMT2AKDM4EALDH1A1MEN1MAPT
SCHEMBL2825786 0.81 ALDH1A1 (0.62) KMT2AKDM4EALDH1A1CASP6POLB
SCHEMBL19119211 0.81 POLB (0.59) KMT2AKDM4EALDH1A1POLBMEN1
SCHEMBL2512589 0.81 LMNA (0.64) KMT2AKDM4EALDH1A1CDC25BCASP6
SCHEMBL28650672 0.81 CA2 (0.49) KMT2AKDM4EALDH1A1POLBMEN1
SCHEMBL11092515 0.81 ALDH1A1 (0.56) KMT2AKDM4EALDH1A1CASP6POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4505913-A Substituted anthranilamides and pharmaceutical preparations containing these compounds CIBA-GEIGY CORPORATION (US) 1985-03-19 US claimed
EP-0008072-B1 SUBSTITUTED ANTHRANILIC ACID AMIDES, PROCESS FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR PREPARATION CIBA-GEIGY AG (CH) 1984-02-22 EP claimed
US-7326288-B2 Trisazo compound, ink composition, and colored object NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2008-02-05 US disclosed
US-20070107628-A1 Trisazo compound, ink composition, and colored object NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2007-05-17 US disclosed
CN-1886467-A Trisazo compound, ink composition, and colored body NIPPON KAYAKU KK (JP) 2006-12-27 CN disclosed
EP-1693422-A1 TRISAZO COMPOUND, INK COMPOSITION, AND COLORED OBJECT Nippon Kayaku Kabushiki Kaisha (JP) 2006-08-23 EP disclosed
EP-0374815-B1 Complex copper formazane compounds, process for their preparation and their use as dyestuffs HOECHST AG (DE) 1994-05-04 EP disclosed
US-5028700-A For cotton, wool, polyamide, red, violet HOECHST AKTIENGESELLSCHAFT (DE) 1991-07-02 US disclosed
EP-0374815-A1 Complex copper formazane compounds, process for their preparation and their use as dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1990-06-27 EP disclosed
US-4505913-A Substituted anthranilamides and pharmaceutical preparations containing these compounds CIBA-GEIGY CORPORATION (US) 1985-03-19 US disclosed
EP-0008072-B1 SUBSTITUTED ANTHRANILIC ACID AMIDES, PROCESS FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR PREPARATION CIBA-GEIGY AG (CH) 1984-02-22 EP disclosed
EP-0008072-A1 Substituted anthranilic acid amides, process for their preparation, pharmaceutical compositions containing them and their preparation CIBA-GEIGY AG (CH) 1980-02-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070107628-A1 Trisazo compound, ink composition, and colored object UFL1, TMT1A, JAK1 KMT2A 588/4885KDM4E 848/4885ALDH1A1 1635/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.