SCHEMBL28651276

SCHEMBL28651276

CCCCC(=S)ONC(=O)OC(C)(C)C

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CTSK P43235 8/20 0.40
CA12 O43570 3/20 0.37
CA1 P00915 3/20 0.37
CA7 P43166 1/20 0.37
CA14 Q9ULX7 1/20 0.37
CA2 P00918 2/20 0.37
CA9 Q16790 2/20 0.37
CTSS P25774 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
MAOA P21397 1/20 0.36
MAOB P27338 1/20 0.36
GAA P10253 3/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
APLNR P35414 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28469830 0.95 CTSK (0.38) CTSKCA12CA1CA7CA14
SCHEMBL1638343 0.83 CTSK (0.43) CTSKCA12CA1CA7CA14
SCHEMBL4653239 0.78 DGKA (0.43) CTSKCA12CA1CA7CA14
SCHEMBL25438156 0.77 DGKA (0.46) CTSKTDP1
SCHEMBL30516551 0.77 DGKA (0.46) CTSKTDP1
SCHEMBL20503257 0.77 DGKA (0.46) CTSKTDP1
SCHEMBL8002118 0.77 DGKA (0.46) CTSKTDP1
SCHEMBL31088250 0.77 DGKA (0.46) CTSKTDP1
SCHEMBL377844 0.75 ALDH1A1 (0.41) CTSKCA12CA1CA7CA14
SCHEMBL21815667 0.75 GAA (0.45) CTSKCA12CA1CA7CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113727986-A Cyclic panthenol derivative and use thereof 彗星医疗股份有限公司 2021-11-30 CN disclosed