Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 2/20 | 0.34 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.33 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.33 |
| ▸ | MERTK | Q12866 | 4/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | AXL | P30530 | 1/20 | 0.31 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24267921 | 0.94 | YTHDC1 (0.38) | GRM2YTHDC1PKMKAT2BNPBWR1 | |
| SCHEMBL29389528 | 0.94 | YTHDC1 (0.38) | GRM2YTHDC1PKMKAT2BNPBWR1 | |
| SCHEMBL27156541 | 0.93 | MERTK (0.40) | GRM2YTHDC1ADORA2AMERTKADORA1 | |
| SCHEMBL27156539 | 0.93 | MERTK (0.40) | GRM2YTHDC1ADORA2AMERTKADORA1 | |
| SCHEMBL10167368 | 0.93 | LMNA (0.36) | YTHDC1KAT2BNPBWR1MERTKLRRK2 | |
| SCHEMBL31299819 | 0.92 | PKM (0.43) | GRM2YTHDC1PKMKAT2BNPBWR1 | |
| SCHEMBL342889 | 0.85 | MITF (0.38) | ADORA2AADORA1ADORA3CRHR1NR3C1 | |
| SCHEMBL342887 | 0.85 | MITF (0.38) | ADORA2AADORA1ADORA3CRHR1NR3C1 | |
| SCHEMBL29819776 | 0.84 | — | — | |
| SCHEMBL27156842 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113429411-A | Preparation method of 1-alkyl-6-chloro-1H-pyrazolo [3,4-d ] pyrimidine compound | 韶远科技（上海)有限公司 | 2021-09-24 | — | — | CN | disclosed |