Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Napropamide SCHEMBL6904715 | 0.99 | TSHR (0.58) | TSHRSMN1; SMN2NPC1MAPTRAB9A | |
| Napropamide SCHEMBL29349502 | 0.99 | TSHR (0.58) | TSHRSMN1; SMN2NPC1MAPTRAB9A | |
| Napropamide SCHEMBL6904717 | 0.99 | TSHR (0.58) | TSHRSMN1; SMN2NPC1MAPTRAB9A | |
| Napropamide SCHEMBL54956 | 0.99 | TSHR (0.58) | TSHRSMN1; SMN2NPC1MAPTRAB9A | |
| Napropamide SCHEMBL29350504 | 0.99 | TSHR (0.58) | TSHRSMN1; SMN2NPC1MAPTRAB9A | |
| Napropamide SCHEMBL2483381 | 0.99 | TSHR (0.58) | TSHRSMN1; SMN2NPC1MAPTRAB9A | |
| Napropamide SCHEMBL2234482 | 0.93 | TSHR (0.53) | TSHRSMN1; SMN2NPC1MAPTRAB9A | |
| Napropamide SCHEMBL28243889 | 0.90 | TSHR (0.50) | TSHRSMN1; SMN2NPC1MAPTRAB9A | |
| Napropamide SCHEMBL11171903 | 0.87 | TSHR (0.47) | TSHRSMN1; SMN2NPC1MAPTRAB9A | |
| Napropamide SCHEMBL8830555 | 0.84 | ALDH1A1 (0.58) | TSHRSMN1; SMN2NPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113614079-A | Crystals of heterocyclic amide compound and process for producing the same | 日产化学株式会社 | 2021-11-05 | — | — | CN | disclosed |