Napropamide

Napropamide

SCHEMBL6904717

CCN(CC)C(=O)[C@H](C)Oc1cccc2ccccc12

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 1/20 0.58
▸ SMN1; SMN2 Q16637 2/20 0.46
▸ NPC1 O15118 1/20 0.46
▸ MAPT P10636 1/20 0.46
▸ RAB9A P51151 1/20 0.46
▸ LMNA P02545 1/20 0.46
▸ ALDH1A1 P00352 5/20 0.44
▸ KDM4E B2RXH2 4/20 0.44
▸ HPGD P15428 2/20 0.44
▸ TDP1 Q9NUW8 1/20 0.44
▸ HSD17B10 Q99714 2/20 0.43
▸ PGR P06401 1/20 0.43
▸ GAA P10253 1/20 0.43
▸ PTGS1 P23219 1/20 0.43
▸ MAPK1 P28482 1/20 0.43
▸ PPARG P37231 2/20 0.43
▸ PPARA Q07869 2/20 0.43
▸ MEN1 O00255 1/20 0.42
▸ CYP1A2 P05177 1/20 0.42
▸ CYP2C19 P33261 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Napropamide SCHEMBL6904715 1.00 TSHR (0.58) TSHRSMN1; SMN2NPC1MAPTRAB9A
Napropamide SCHEMBL2483381 1.00 TSHR (0.58) TSHRSMN1; SMN2NPC1MAPTRAB9A
Napropamide SCHEMBL29349502 1.00 TSHR (0.58) TSHRSMN1; SMN2NPC1MAPTRAB9A
Napropamide SCHEMBL29350504 1.00 TSHR (0.58) TSHRSMN1; SMN2NPC1MAPTRAB9A
Napropamide SCHEMBL54956 1.00 TSHR (0.58) TSHRSMN1; SMN2NPC1MAPTRAB9A
Napropamide SCHEMBL28652387 0.99 TSHR (0.57) TSHRSMN1; SMN2NPC1MAPTRAB9A
Napropamide SCHEMBL2234482 0.95 TSHR (0.53) TSHRSMN1; SMN2NPC1MAPTRAB9A
Napropamide SCHEMBL28243889 0.91 TSHR (0.50) TSHRSMN1; SMN2NPC1MAPTRAB9A
Napropamide SCHEMBL11171903 0.88 TSHR (0.47) TSHRSMN1; SMN2NPC1MAPTRAB9A
Napropamide SCHEMBL8830555 0.85 ALDH1A1 (0.58) TSHRSMN1; SMN2NPC1MAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-1146807-A — — None — — JP disclosed
EP-4742898-A1 HERBICIDE SAFENER COMBINATIONS AND COMPOSITIONS UPL Mauritius Limited (MU) 2026-05-20 — — EP disclosed
US-20250081966-A1 HERBICIDE COMBINATIONS UPL Corporation Limited (MU) 2025-03-13 — — US disclosed
WO-2025012825-A1 HERBICIDE SAFENER COMBINATIONS AND COMPOSITIONS UPL MAURITIUS LIMITED (MU) 2025-01-16 — — WO disclosed
US-20210360922-A1 HERBICIDAL COMBINATIONS UPL LTD (IN) 2021-11-25 — — US disclosed
EP-3319439-B1 HERBICIDAL COMPOSITION COMPRISING CINMETHYLIN AND NAPROPAMIDE BASF AGRO BV (NL) 2019-04-24 — — EP disclosed
US-6677276-B1 COMPRISES GLUFOSINATE-AMMONIUM IN COMBINATION WITH AT LEAST ONE HERBICIDE IN SYNERGISTIC MIXTURE AVENTIS CROPSCIENCE GMBH (DE) 2004-01-13 — — US disclosed
US-6498126-B1 Herbicide combination with acylated aminophenylsulfonylureas AVENTIS CROPSCIENCE GMBH (DE) 2002-12-24 — — US disclosed
EP-0202169-B1 NEW PYRAZOLE DERIVATIVES, THEIR PRODUCTION AND USES HOKKO CHEMICAL INDUSTRY CO., LTD (JP) 1992-11-19 — — EP disclosed
JP-H01146807-A WEEDING METHOD USING DIFLUFENICAN MAY & BAKER LTD 1989-06-08 — — JP disclosed
US-4752326-A 1-arylpyrazoles, composition containing them, and herbicidal method of using them HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) 1988-06-21 — — US disclosed
EP-0202169-A1 New pyrazole derivatives, their production and uses HOKKO CHEMICAL INDUSTRY CO., LTD (JP) 1986-11-20 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250081966-A1 HERBICIDE COMBINATIONS PRXL2A, NAPEPLD, PRDX6 TSHR 4304/4885SMN1; SMN2 4200/4885NPC1 4380/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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