Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | ACHE | P22303 | 1/20 | 0.58 |
| ▸ | PGR | P06401 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Napropamide SCHEMBL29350504 | 0.85 | TSHR (0.58) | ALDH1A1PGRGAAPTGS1MAPK1 | |
| Napropamide SCHEMBL54956 | 0.85 | TSHR (0.58) | ALDH1A1PGRGAAPTGS1MAPK1 | |
| Napropamide SCHEMBL2483381 | 0.85 | TSHR (0.58) | ALDH1A1PGRGAAPTGS1MAPK1 | |
| Napropamide SCHEMBL6904715 | 0.85 | TSHR (0.58) | ALDH1A1PGRGAAPTGS1MAPK1 | |
| Napropamide SCHEMBL29349502 | 0.85 | TSHR (0.58) | ALDH1A1PGRGAAPTGS1MAPK1 | |
| Napropamide SCHEMBL6904717 | 0.85 | TSHR (0.58) | ALDH1A1PGRGAAPTGS1MAPK1 | |
| Napropamide SCHEMBL28652387 | 0.84 | TSHR (0.57) | ALDH1A1PGRGAAPTGS1MAPK1 | |
| Napropamide SCHEMBL8830547 | 0.82 | ALDH1A1 (0.44) | ALDH1A1ACHEPGRGAAPTGS1 | |
| Napropamide SCHEMBL8830476 | 0.81 | ALDH1A1 (0.45) | ALDH1A1ACHEPGRGAAPTGS1 | |
| Napropamide SCHEMBL2234482 | 0.81 | TSHR (0.53) | ALDH1A1PGRGAAPTGS1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5656422-A | HYDRATING A DRIED ENZYME TO PRODUCE HYDRATED ENZYME, CONTACTING WITH SAMPLE TO DETECT PRESENCE OF PHENOLIC PRODUCTS FORMED BY CLEAVAGE OF PHENOLIC ETHER BOND BY THE ENZYME | IDAHO RESEARCH FOUNDATION, INC. (US) | 1997-08-12 | — | — | US | disclosed |