Napropamide

Napropamide

SCHEMBL6904715

CCN(CC)C(=O)[C@@H](C)Oc1cccc2ccccc12

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 1/20 0.58
▸ SMN1; SMN2 Q16637 2/20 0.46
▸ NPC1 O15118 1/20 0.46
▸ MAPT P10636 1/20 0.46
▸ RAB9A P51151 1/20 0.46
▸ LMNA P02545 1/20 0.46
▸ ALDH1A1 P00352 5/20 0.44
▸ KDM4E B2RXH2 4/20 0.44
▸ HPGD P15428 2/20 0.44
▸ TDP1 Q9NUW8 1/20 0.44
▸ HSD17B10 Q99714 2/20 0.43
▸ PGR P06401 1/20 0.43
▸ GAA P10253 1/20 0.43
▸ PTGS1 P23219 1/20 0.43
▸ MAPK1 P28482 1/20 0.43
▸ PPARG P37231 2/20 0.43
▸ PPARA Q07869 2/20 0.43
▸ MEN1 O00255 1/20 0.42
▸ CYP1A2 P05177 1/20 0.42
▸ CYP2C19 P33261 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Napropamide SCHEMBL6904717 1.00 TSHR (0.58) TSHRSMN1; SMN2NPC1MAPTRAB9A
Napropamide SCHEMBL2483381 1.00 TSHR (0.58) TSHRSMN1; SMN2NPC1MAPTRAB9A
Napropamide SCHEMBL29349502 1.00 TSHR (0.58) TSHRSMN1; SMN2NPC1MAPTRAB9A
Napropamide SCHEMBL29350504 1.00 TSHR (0.58) TSHRSMN1; SMN2NPC1MAPTRAB9A
Napropamide SCHEMBL54956 1.00 TSHR (0.58) TSHRSMN1; SMN2NPC1MAPTRAB9A
Napropamide SCHEMBL28652387 0.99 TSHR (0.57) TSHRSMN1; SMN2NPC1MAPTRAB9A
Napropamide SCHEMBL2234482 0.95 TSHR (0.53) TSHRSMN1; SMN2NPC1MAPTRAB9A
Napropamide SCHEMBL28243889 0.91 TSHR (0.50) TSHRSMN1; SMN2NPC1MAPTRAB9A
Napropamide SCHEMBL11171903 0.88 TSHR (0.47) TSHRSMN1; SMN2NPC1MAPTRAB9A
Napropamide SCHEMBL8830555 0.85 ALDH1A1 (0.58) TSHRSMN1; SMN2NPC1MAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 209 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0292154-B1 HERBICIDAL METHOD USING DIFLUFENICAN MAY & BAKER LIMITED (GB) 1992-04-15 — — EP claimed
JP-1146807-A — — None — — JP disclosed
US-20260098020-A1 HERBICIDAL PYRIMIDINYLMETHYL-SUBSTITUTED 1,2,4-TRIAZOLES FMC CORP (US) 2026-04-09 — — US disclosed
EP-4714942-A1 SUBSTITUTED HALOALKYL SULFONANILIDE HERBICIDES FMC Corporation (US) 2026-03-25 — — EP disclosed
US-12552752-B2 Atropisomers of pyridazinone derivatives as herbicides FMC CORPORATION (US) 2026-02-17 — — US disclosed
EP-4683908-A1 SUBSTITUTED OXAZOLIDINONES AND IMIDAZOLINONES AS HERBICIDES FMC Corporation (US) 2026-01-28 — — EP disclosed
EP-4188093-B9 SUBSTITUTED HALOALKYL SULFONANILIDE HERBICIDES FMC CORP (US) 2025-12-03 — — EP disclosed
US-12435044-B2 Pyridazinone herbicides and pyridazinone intermediates used to prepare a herbicide FMC CORPORATION (US) 2025-10-07 — — US disclosed
EP-4188093-B1 SUBSTITUTED HALOALKYL SULFONANILIDE HERBICIDES FMC CORP (US) 2025-09-03 — — EP disclosed
WO-2025111184-A1 SUBSTITUTED TETRAHYDROQUINOLINE AND TETRAHYDROQUINOXALINE HERBICIDES FMC CORPORATION (US) 2025-05-30 — — WO disclosed
CN-101677538-A Process for manufacture of high purity d-(-)-n,n-diethyl-2-(alpha-naphthoxy) propionamide UNITED PHOSPHORUS LTD 2010-03-24 — — CN disclosed
US-6677276-B1 COMPRISES GLUFOSINATE-AMMONIUM IN COMBINATION WITH AT LEAST ONE HERBICIDE IN SYNERGISTIC MIXTURE AVENTIS CROPSCIENCE GMBH (DE) 2004-01-13 — — US disclosed
EP-1104241-B1 HERBICIDES FOR TOLERANT OR RESISTANT OIL SEED RAPE CULTURES BAYER CROPSCIENCE GMBH (DE) 2003-06-18 — — EP disclosed
EP-1231839-B1 HERBICIDE MEANS WITH ACYLATED AMINO PHENYL SULFONYL CARBAMIDE BAYER CROPSCIENCE GMBH (DE) 2003-05-14 — — EP disclosed
US-6498126-B1 Herbicide combination with acylated aminophenylsulfonylureas AVENTIS CROPSCIENCE GMBH (DE) 2002-12-24 — — US disclosed
EP-1231839-A2 HERBICIDE MEANS WITH ACYLATED AMINO PHENYL SULFONYL CARBAMIDE Aventis CropScience GmbH (DE) 2002-08-21 — — EP disclosed
EP-1104241-A1 HERBICIDES FOR TOLERANT OR RESISTANT OIL SEED RAPE CULTURES Aventis CropScience GmbH (DE) 2001-06-06 — — EP disclosed
WO-2001035742-A2 HERBICIDE MEANS WITH ACYLATED AMINO PHENYL SULFONYL CARBAMIDE AVENTIS CROPSCIENCE GMBH (DE) 2001-05-25 — — WO disclosed
WO-2000008938-A1 HERBICIDES FOR TOLERANT OR RESISTANT OIL SEED RAPE CULTURES AVENTIS CROPSCIENCE GMBH (DE) 2000-02-24 — — WO disclosed
JP-H01146807-A WEEDING METHOD USING DIFLUFENICAN MAY & BAKER LTD 1989-06-08 — — JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12435044-B2 Pyridazinone herbicides and pyridazinone intermediates used to prepare a herbicide CBR3, CBR1, CYP4F3 TSHR 683/4885SMN1; SMN2 4796/4885NPC1 4592/4885
US-12552752-B2 Atropisomers of pyridazinone derivatives as herbicides CBR3, TDO2, FOXO3 TSHR 435/4885SMN1; SMN2 2260/4885NPC1 4332/4885
US-20260098020-A1 HERBICIDAL PYRIMIDINYLMETHYL-SUBSTITUTED 1,2,4-TRIAZOLES CBR3, CBR1, CNPY3 TSHR 2437/4885SMN1; SMN2 4537/4885NPC1 1540/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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