SCHEMBL2865480

SCHEMBL2865480

CC(Cl)c1ccc(C(C)Cl)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 1/20 0.41
ESR1 P03372 1/20 0.38
PDCD1 Q15116 1/20 0.38
ESR2 Q92731 1/20 0.38
CD274 Q9NZQ7 1/20 0.38
TSHR P16473 4/20 0.36
MAPK1 P28482 2/20 0.36
TDP1 Q9NUW8 2/20 0.36
HIF1A Q16665 1/20 0.36
ATM Q13315 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
ALDH1A1 P00352 1/20 0.36
PGK1 P00558 1/20 0.35
PGK2 P07205 1/20 0.35
TYR P14679 2/20 0.33
LMNA P02545 1/20 0.32
HTT P42858 1/20 0.31
TRPA1 O75762 1/20 0.31
PTGS1 P23219 1/20 0.31
CACNA1C Q13936 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30471741 0.90 TYR (0.46) ADRB2TSHRMAPK1TDP1HIF1A
SCHEMBL8750387 0.90 TYR (0.46) ADRB2TSHRMAPK1TDP1HIF1A
SCHEMBL678428 0.87 ADRB2 (0.59) ADRB2TSHRMAPK1TDP1HIF1A
SCHEMBL897929 0.87 ACHE (0.47) ADRB2TSHRTDP1ALDH1A1LMNA
SCHEMBL677868 0.85 MEN1 (0.44) ADRB2TSHRMAPK1TDP1HIF1A
SCHEMBL677814 0.85 ESR1 (0.62) ESR1PDCD1ESR2CD274TSHR
SCHEMBL930683 0.85 IDO1 (0.42) ADRB2ALDH1A1HTTTRPA1
SCHEMBL9320410 0.85 IDO1 (0.41) ADRB2ESR1PDCD1ESR2CD274
SCHEMBL17497526 0.85 ADRB2 (0.33) ADRB2ESR1PDCD1ESR2CD274
SCHEMBL3165206 0.85 CYP2A6 (0.44) MAPK1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110343197-A A kind of preparation method and its antibacterial application of polymeric quaternary ammonium salt photochemical catalyst 浙江大学 2019-10-18 CN claimed
CN-104974293-B Cationic polymerization method 中国石油化工股份有限公司 2018-04-10 CN disclosed
US-7718588-B2 Lubricating oil additive containing acrylic polymer and lubricating oil compositions KURARAY CO., LTD. (JP) 2010-05-18 US disclosed
US-20080058234-A1 Lubricating Oil Additive Containing Acrylic Polymer and Lubricating Oil Compositions KURARAY CO., LTD. (JP) 2008-03-06 US disclosed
US-6716918-B2 ATOM TRANSFER RADICAL POLYMERIZATION IN THE PRESENCE OF A REDOX CATALYST OF A TRANSITION METAL COMPLEX ALSO USING AN ORGANOHALOGEN OR HALOGENATED SULFONYL COMPOUND AS A POLYMERIZATION CATALYST MITSUBISHI CHEMICAL CORPORATION (JP) 2004-04-06 US disclosed
WO-2003078498-A1 ELECTRONICALLY CONDUCTIVE PPV COPOLYMERS RISØ NATIONAL LABORATORY (DK) 2003-09-25 WO disclosed
US-20020156196-A1 Methacrylate-based polymer and process for producing the same MITSUBISHI CHEMICAL CORPORATION (JP) 2002-10-24 US disclosed
EP-0816385-B1 Process for preparing vinyl polymer KANEKA CORP (JP) 2002-01-30 EP disclosed
US-6336966-B1 DISPERSION COMPRISING PIGMENT, WATER OR MIXTURE OF WATER AND ORGANIC SOLVENT AS CARRIER, DISPERSANT PREPARED BY ATOM TRANSFER RADICAL POLYMERIZATION OF UNSATURATED MONOMERS AND HAVING HYDROPHILIC AND HYDROPHOBIC SEGMENTS IN EACH ARM PPG INDUSTRIES OHIO, INC. 2002-01-08 US disclosed
US-6326420-B1 AQUEOUS CARRIER PPG INDUSTRIES OHIO, INC. 2001-12-04 US disclosed
US-6291612-B1 POLYMERIZING VINYL MONOMER SUCH AS ACRYLATES AND METHACRYLATES USING AN ORGANIC HALIDE POLYMERIZATION INITIATOR IN THE PRESENCE OF A CUPROUS COMPOUND CATALYST IN A SOLVENT KANEKO CORPORATION (JP) 2001-09-18 US disclosed
EP-0816385-A1 Process for preparing vinyl polymer Kaneka Corporation (JP) 1998-01-07 EP disclosed
EP-0032062-B2 HIGH-MOLECULAR-WEIGHT NOVOLAK SUBSTITUTED PHENOLIC RESINS AND THEIR PREPARATION MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-10-16 EP disclosed
EP-0032062-B1 HIGH-MOLECULAR-WEIGHT NOVOLAK SUBSTITUTED PHENOLIC RESINS AND THEIR PREPARATION MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1985-04-03 EP disclosed
US-4345054-A High-molecular-weight novolak types substituted phenolic resins and process for preparation thereof MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1982-08-17 US disclosed