Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30471741 | 1.00 | TYR (0.46) | TYRHTTADRB2IDO1NFKB1 | |
| SCHEMBL2865480 | 0.90 | ADRB2 (0.41) | TYRHTTADRB2NFKB1LMNA | |
| SCHEMBL678428 | 0.85 | ADRB2 (0.59) | ADRB2IDO1LMNACYP2C9HIF1A | |
| SCHEMBL104124 | 0.83 | TYR (0.58) | TYRHTTADRB2IDO1NFKB1 | |
| SCHEMBL677868 | 0.82 | MEN1 (0.44) | HTTADRB2HIF1AMAPK1TSHR | |
| SCHEMBL1462968 | 0.81 | TSHR (0.50) | TYRHTTADRB2IDO1NFKB1 | |
| Water SCHEMBL11726962 | 0.79 | TYR (0.55) | TYRHTTADRB2IDO1NFKB1 | |
| Ammonia Solution, Strong SCHEMBL7550588 | 0.79 | TYR (0.55) | TYRHTTADRB2IDO1NFKB1 | |
| SCHEMBL28912214 | 0.79 | TYR (0.55) | TYRHTTADRB2IDO1NFKB1 | |
| Water SCHEMBL29278796 | 0.79 | TYR (0.55) | TYRHTTADRB2IDO1NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230373927-A1 | 6-METHOXY-3,4-DIHYDRO-1H-ISOQUINOLIN COMPOUNDS | ELI LILLY AND COMPANY | 2023-11-23 | — | — | US | disclosed |
| EP-4225738-A1 | 6-METHOXY-3,4-DIHYDRO-1H-ISOQUINOLINE COMPOUNDS USEFUL IN THE TREATMENT OF DIABETES | Eli Lilly and Company (US) | 2023-08-16 | — | — | EP | disclosed |
| CN-116323561-A | 6-methoxy-3, 4-dihydro-1H-isoquinoline compounds useful in the treatment of diabetes | 伊莱利利公司 | 2023-06-23 | — | — | CN | disclosed |
| US-20210188845-A1 | SUBSTITUTED BICYCLIC COMPOUNDS USEFUL AS T CELL ACTIVATORS | BRISTOL-MYERS SQUIBB COMPANY | 2021-06-24 | — | — | US | disclosed |
| WO-2021041588-A1 | SUBSTITUTED PYRIDOPYRIMIDINONYL COMPOUNDS USEFUL AS T CELL ACTIVATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2021-03-04 | — | — | WO | disclosed |
| EP-1849787-A1 | Organosilicon compound | Chisso Corporation (JP) | 2007-10-31 | — | — | EP | disclosed |
| EP-0523697-B1 | Color-developing compositions and their use | MITSUI TOATSU CHEMICALS (JP) | 1997-04-02 | — | — | EP | disclosed |
| EP-0470516-B1 | Process for producing 3,5-di(alpha-methylbenzyl)salicylic acid derivative, and use of polyvalent-metal-modified product thereof as color developer | MITSUI TOATSU CHEMICALS (JP) | 1996-03-06 | — | — | EP | disclosed |
| EP-0268878-B1 | Salicylic acid copolymers and their metal salts, production process thereof, color-developing agents comprising metal salts of the copolymers and color-developing sheets employing the agents | MITSUI TOATSU CHEMICALS (JP) | 1996-01-31 | — | — | EP | disclosed |
| US-5447901-A | Color-developing sheet: base material coated with composition of /a/ multivalent metal-modified salicylic acid resin formed from salicylic acid, a benzyl compound and optional styrene and /b/ analogous resin free of salicylic acid | MITSUI TOATSU CHEMICAL, INC. (JP) | 1995-09-05 | — | — | US | disclosed |
| EP-0361040-B1 | Odorless multi-valent metal modified products of salicylic acid copolymers, production processes thereof, and use thereof as color-developing agents for pressure-sensitive copying paper sheets | MITSUI TOATSU CHEMICALS (JP) | 1994-12-07 | — | — | EP | disclosed |
| US-5326739-A | Process for producing 3,5-di(α-methylbenzyl)salicylic acid derivative, and use of polyvalent-metal-modified product thereof as color developer | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1994-07-05 | — | — | US | disclosed |
| US-5274150-A | Reacting a salicyclic acid ester with an alpha-methyl-benzyl halide using an acid catalyst and hydrolyzing | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1993-12-28 | — | — | US | disclosed |
| EP-0523697-A1 | Color-developing compositions and their use | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1993-01-20 | — | — | EP | disclosed |
| EP-0470516-A2 | Process for producing 3,5-di(alpha-methylbenzyl)salicylic acid derivative, and use of polyvalent-metal-modified product thereof as color developer | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1992-02-12 | — | — | EP | disclosed |
| US-5028581-A | Odorless multi-valent metal modified products of salicyclic acid copolymers, production processes thereof, and use thereof as color-developing agents for pressure-sensitive copying paper sheets | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1991-07-02 | — | — | US | disclosed |
| US-5023366-A | Reacted with a benzyl halide, alcohol or ether; for pressure sensitive elements | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1991-06-11 | — | — | US | disclosed |
| EP-0361040-A2 | Odorless multi-valent metal modified products of salicylic acid copolymers, production processes thereof, and use thereof as color-developing agents for pressure-sensitive copying paper sheets | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1990-04-04 | — | — | EP | disclosed |
| CN-1040377-A | Polyvalent metal modification odorlessness product manufacture method of salicylic acid copolymers and uses thereof | MITSUI TOATSU CHEMICALS (JP) | 1990-03-14 | — | — | CN | disclosed |
| EP-0268878-A2 | Salicylic acid copolymers and their metal salts, production process thereof, color-developing agents comprising metal salts of the copolymers and color-developing sheets employing the agents | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1988-06-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230373927-A1 | 6-METHOXY-3,4-DIHYDRO-1H-ISOQUINOLIN COMPOUNDS | GLP1R, GIPR, GPR119 | TYR 928/4885HTT 654/4885ADRB2 325/4885 |
| US-20210188845-A1 | SUBSTITUTED BICYCLIC COMPOUNDS USEFUL AS T CELL ACTIVATORS | DGKA, DGKZ, DGKK | TYR 2603/4885HTT 4797/4885ADRB2 2051/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.