Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28664297 | 0.90 | MAPT (0.40) | HPGDPOLBHTTMAPTALDH1A1 | |
| SCHEMBL28670315 | 0.88 | MAPT (0.47) | HPGDMAPTALDH1A1NPSR1KCNH2 | |
| SCHEMBL30271525 | 0.86 | MAPT (0.39) | HPGDPOLBHTTMAPTALDH1A1 | |
| SCHEMBL28658947 | 0.85 | KCNH2 (0.37) | KCNH2CACNA1IMEN1KMT2AGRN | |
| SCHEMBL28664307 | 0.85 | HPGD (0.38) | HPGDPOLBHTTMAPTALDH1A1 | |
| SCHEMBL28668938 | 0.81 | SMPD1 (0.36) | POLBMAPTNPSR1KCNH2NPC1 | |
| SCHEMBL28671206 | 0.81 | NTRK1 (0.37) | POLBMAPTKDM4E | |
| SCHEMBL28656141 | 0.80 | ALDH1A1 (0.39) | HPGDMAPTALDH1A1NPSR1KCNH2 | |
| SCHEMBL28654023 | 0.80 | HDAC3 (0.43) | MAPTALDH1A1NPSR1CYP1A2CYP2C9 | |
| SCHEMBL28673180 | 0.80 | KDM4E (0.42) | POLBMAPTALDH1A1CYP1A2RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113692276-A | NURR1 receptor modulators | 加利福尼亚大学董事会 | 2021-11-23 | — | — | CN | disclosed |