Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | FLT1 | P17948 | 1/20 | 0.35 |
| ▸ | FLT4 | P35916 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.35 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28649850 | 0.87 | KCNH2 (0.35) | KMT2AMEN1PTGS2FLT1FLT4 | |
| SCHEMBL28655200 | 0.85 | HPGD (0.43) | HPGDMAPTKMT2AALDH1A1MEN1 | |
| SCHEMBL28664297 | 0.84 | MAPT (0.40) | HPGDMAPTKMT2AALDH1A1MEN1 | |
| SCHEMBL28654355 | 0.83 | PTGS2 (0.33) | PTGS2KCNH2 | |
| SCHEMBL28650916 | 0.83 | GAA (0.38) | MAPTKMT2AALDH1A1MEN1RECQL | |
| SCHEMBL28650412 | 0.82 | GLS (0.38) | ALDH1A1CNR1 | |
| SCHEMBL28670315 | 0.82 | MAPT (0.47) | HPGDMAPTKMT2AALDH1A1MEN1 | |
| SCHEMBL28929387 | 0.82 | TAS2R8 (0.38) | MAPTKMT2AALDH1A1MEN1PTGS2 | |
| SCHEMBL30271525 | 0.80 | MAPT (0.39) | HPGDMAPTKMT2AALDH1A1MEN1 | |
| SCHEMBL28654148 | 0.79 | BCAT1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113692276-A | NURR1 receptor modulators | 加利福尼亚大学董事会 | 2021-11-23 | — | — | CN | disclosed |