Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 1/20 | 0.37 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.37 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.37 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | SMPD1 | P17405 | 4/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | MDM4 | O15151 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28650423 | 0.89 | ALK (0.34) | NTRK1NTRK3NTRK2ALKDPP4 | |
| SCHEMBL28658949 | 0.86 | DPP4 (0.38) | ALKDPP4CTSLCTSSSLC6A3 | |
| SCHEMBL28668938 | 0.86 | SMPD1 (0.36) | SMPD1MAPK14POLBMAPTCTSL | |
| SCHEMBL28658947 | 0.86 | KCNH2 (0.37) | — | |
| SCHEMBL30271516 | 0.85 | HDAC3 (0.34) | ALKDPP4POLBMAPTCTSL | |
| SCHEMBL28673180 | 0.85 | KDM4E (0.42) | POLBMAPTTP53KDM4E | |
| SCHEMBL28655200 | 0.81 | HPGD (0.43) | POLBMAPTKDM4E | |
| SCHEMBL28670344 | 0.79 | MAPT (0.34) | MAPK14MAPT | |
| SCHEMBL28664287 | 0.76 | CACNA1H (0.39) | — | |
| SCHEMBL28676235 | 0.76 | ALDH1A1 (0.38) | SMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113692276-A | NURR1 receptor modulators | 加利福尼亚大学董事会 | 2021-11-23 | — | — | CN | disclosed |