Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | ERN1 | O75460 | 10/20 | 0.53 |
| ▸ | CGAS | Q8N884 | 2/20 | 0.51 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.50 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.50 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.50 |
| ▸ | ABAT | P80404 | 1/20 | 0.50 |
| ▸ | PRKDC | P78527 | 2/20 | 0.48 |
| ▸ | TYR | P14679 | 1/20 | 0.46 |
| ▸ | TLR2 | O60603 | 1/20 | 0.46 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.46 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29953159 | 0.92 | ERN1 (0.53) | ALDH1A1TDP1KDM4ETSHRERN1 | |
| SCHEMBL5355474 | 0.92 | ERN1 (0.53) | ALDH1A1TDP1KDM4ETSHRERN1 | |
| SCHEMBL3641916 | 0.85 | ALDH1A1 (0.53) | ALDH1A1TDP1KDM4ETSHRERN1 | |
| SCHEMBL1002368 | 0.84 | ALDH1A1 (0.69) | ALDH1A1TDP1KDM4ETSHRERN1 | |
| SCHEMBL29459687 | 0.84 | ALDH1A1 (0.57) | ALDH1A1TDP1KDM4ETSHRERN1 | |
| SCHEMBL1004432 | 0.84 | ALDH1A1 (0.57) | ALDH1A1TDP1KDM4ETSHRERN1 | |
| SCHEMBL29459727 | 0.84 | ALDH1A1 (0.69) | ALDH1A1TDP1KDM4ETSHRERN1 | |
| SCHEMBL1494078 | 0.84 | ALDH1A1 (0.68) | ALDH1A1TDP1KDM4ETSHRERN1 | |
| SCHEMBL24311483 | 0.82 | ALDH1A1 (0.72) | ALDH1A1TDP1KDM4ETSHRERN1 | |
| SCHEMBL697093 | 0.82 | ALDH1A1 (0.59) | ALDH1A1TDP1KDM4ETSHRERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111548260-A | Separation method of 6-methyl vanillin and vanillin | 上海欣晨新技术有限公司 | 2020-08-18 | — | — | CN | claimed |
| US-20210289794-A1 | COMPOSITIONS AND RELATED METHODS FOR AGRICULTURE | FLAGSHIP PIONEERING INNOVATIONS V, INC. | 2021-09-23 | — | — | US | disclosed |
| US-10947206-B2 | cGAS antagonist compounds | IMMUNESENSOR THERAPEUTICS, INC. (US) | 2021-03-16 | — | — | US | disclosed |
| CN-111548260-A | Separation method of 6-methyl vanillin and vanillin | 上海欣晨新技术有限公司 | 2020-08-18 | — | — | CN | disclosed |
| CN-111548260-A | Separation method of 6-methyl vanillin and vanillin | 上海欣晨新技术有限公司 | 2020-08-18 | — | — | CN | disclosed |
| CN-111548260-A | Separation method of 6-methyl vanillin and vanillin | 上海欣晨新技术有限公司 | 2020-08-18 | — | — | CN | disclosed |
| WO-2017176812-A1 | cGAS ANTAGONIST COMPOUNDS | IMMUNE SENSOR, LLC (US) | 2017-10-12 | — | — | WO | disclosed |
| US-20160097755-A1 | METHOD FOR DETECTING, CAPTURING AND/OR RELEASING CHEMICAL ELEMENTS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2016-04-07 | — | — | US | disclosed |
| US-9230827-B2 | Method for forming a resist under layer film and patterning process | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2016-01-05 | — | — | US | disclosed |
| EP-2427444-B1 | INHIBITORS OF THE RENAL OUTER MEDULLARY POTASSIUM CHANNEL | MERCK SHARP & DOHME (US) | 2015-12-16 | — | — | EP | disclosed |
| US-20140142115-A1 | INHIBITORS OF THE RENAL OUTER MEDULLARY POTASSIUM CHANNEL | MERCK SHARP & DOHME CORP. (US) | 2014-05-22 | — | — | US | disclosed |
| US-8673920-B2 | Inhibitors of the renal outer medullary potassium channel | MERCK SHARP & DOHME CORP. (US) | 2014-03-18 | — | — | US | disclosed |
| US-20130171569-A1 | RESIST UNDERLAYER FILM COMPOSITION, METHOD FOR PRODUCING POLYMER FOR RESIST UNDERLAYER FILM, AND PATTERNING PROCESS USING THE RESIST UNDERLAYER FILM COMPOSITION | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2013-07-04 | — | — | US | disclosed |
| US-20120184103-A1 | RESIST UNDERLAYER FILM COMPOSITION AND PATTERNING PROCESS USING THE SAME | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2012-07-19 | — | — | US | disclosed |
| EP-2427444-A1 | INHIBITORS OF THE RENAL OUTER MEDULLARY POTASSIUM CHANNEL | Merck Sharp & Dohme Corp. (US) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010129379-A1 | INHIBITORS OF THE RENAL OUTER MEDULLARY POTASSIUM CHANNEL | MERCK SHARP & DOHME CORP. (US) | 2010-11-11 | — | — | WO | disclosed |
| US-20100286123-A1 | INHIBITORS OF THE RENAL OUTER MEDULLARY POTASSIUM CHANNEL | MERCK SHARP & DOHME LLC | 2010-11-11 | — | — | US | disclosed |
| US-20030236439-A1 | Non-steroidal analogs of 2-methoxyestradiol | ENTREMED, INC. | 2003-12-25 | — | — | US | disclosed |
| WO-2003063787-A2 | NON-STEROIDAL ANALOGS OF 2-METHOXYESTRADIOL | ENTREMED, INC. (US) | 2003-08-07 | — | — | WO | disclosed |
| EP-0029617-A1 | Use of tertiary heterocyclic amines as synergists in pesticides; derivatives of cycloamines | C.F. Spiess & Sohn GmbH & Co. Chemische Fabrik (DE) | 1981-06-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10947206-B2 | cGAS antagonist compounds | CGAS, STING1, GLS2 | ALDH1A1 3908/4885TDP1 59/4885KDM4E 4717/4885 |
| US-20030236439-A1 | Non-steroidal analogs of 2-methoxyestradiol | NR5A1, CCNB2, CYP17A1 | ALDH1A1 2518/4885TDP1 3666/4885KDM4E 1441/4885 |
| US-20140142115-A1 | INHIBITORS OF THE RENAL OUTER MEDULLARY POTASSIUM CHANNEL | KCNJ11, KCNJ1, KCNJ2 | ALDH1A1 1376/4885TDP1 3705/4885KDM4E 1977/4885 |
| US-20100286123-A1 | INHIBITORS OF THE RENAL OUTER MEDULLARY POTASSIUM CHANNEL | KCNJ11, KCNJ1, KCNJ2 | ALDH1A1 1376/4885TDP1 3705/4885KDM4E 1977/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.