SCHEMBL1004432

SCHEMBL1004432

COc1cc(C=O)c(O)cc1O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.57
TDP1 Q9NUW8 2/20 0.57
KDM4E B2RXH2 2/20 0.57
TSHR P16473 1/20 0.57
ERN1 O75460 10/20 0.53
TRIM24 O15164 2/20 0.53
TRIM33 Q9UPN9 2/20 0.53
TYR P14679 1/20 0.53
AOX1 Q06278 1/20 0.53
HPGD P15428 1/20 0.53
ALDH5A1 P51649 1/20 0.53
ABAT P80404 1/20 0.53
PRKDC P78527 2/20 0.52
TLR2 O60603 1/20 0.48
TLR1 Q15399 1/20 0.48
TLR6 Q9Y2C9 1/20 0.48
CYP3A4 P08684 1/20 0.46
MAPT P10636 1/20 0.46
ALOX15 P16050 1/20 0.46
HSD17B10 Q99714 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29459687 1.00 ALDH1A1 (0.57) ALDH1A1TDP1KDM4ETSHRERN1
SCHEMBL6234401 0.92 ERN1 (0.53) ALDH1A1TDP1KDM4ETSHRERN1
SCHEMBL29730976 0.89 ALDH1A1 (0.65) ALDH1A1TDP1KDM4ETSHRERN1
SCHEMBL333221 0.89 ALDH1A1 (0.65) ALDH1A1TDP1KDM4ETSHRERN1
SCHEMBL22635018 0.88 ALDH1A1 (0.69) ALDH1A1TDP1KDM4ETSHRERN1
SCHEMBL1002368 0.88 ALDH1A1 (0.69) ALDH1A1TDP1KDM4ETSHRERN1
SCHEMBL29459727 0.88 ALDH1A1 (0.69) ALDH1A1TDP1KDM4ETSHRERN1
SCHEMBL286553 0.84 ALDH1A1 (0.53) ALDH1A1TDP1KDM4ETSHRERN1
SCHEMBL3641916 0.84 ALDH1A1 (0.53) ALDH1A1TDP1KDM4ETSHRERN1
SCHEMBL9818754 0.83 ALDH1A1 (0.63) ALDH1A1TDP1KDM4ETSHRERN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 306 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11918671-B2 Multi-tone hair dyeing method in three steps HENKEL AG & CO. KGAA (DE) 2024-03-05 US claimed
US-20230031764-A1 MULTI-TONE HAIR DYEING METHOD IN THREE STEPS HENKEL AG & CO. KGAA (DE) 2023-02-02 US claimed
US-20220257483-A1 INCREASING THE STABILITY OF AGENTS FOR TREATING KERATIN MATERIAL HENKEL AG & CO. KGAA (DE) 2022-08-18 US claimed
CN-114746069-A Three-step multi-tone hair dyeing method 汉高股份有限及两合公司 2022-07-12 CN claimed
CN-110256389-B Preparation method of hyoscyamine 苏州百灵威超精细材料有限公司 2022-06-14 CN claimed
CN-114173750-A Improving the stability of agents for treating keratin materials 汉高股份有限及两合公司 2022-03-11 CN claimed
WO-2021110306-A1 MULTI-TONE HAIR DYEING METHOD IN THREE STEPS HENKEL AG & CO. KGAA (DE) 2021-06-10 WO claimed
CN-110256389-A The preparation method of gelsemium henbane pavilion 苏州百灵威超精细材料有限公司 2019-09-20 CN claimed
CN-109705078-A The chemical total synthesis method of escoparone 西南大学 2019-05-03 CN claimed
CN-105884733-B A kind of scopoletin and its synthetic method of stable isotope labeling 中国烟草总公司郑州烟草研究院 2018-07-24 CN claimed
WO-2006119821-A1 AGENT FOR DYEING KERATIN-BASED FIBRES HENKEL KOMMANDITGESELLCHAFT AUF AKTIEN (DE) 2006-11-16 WO claimed
WO-2006119818-A1 AGENTS FOR DYEING KERATIN-BASED FIBRES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2006-11-16 WO claimed
WO-2006119819-A1 AGENT FOR DYEING KERATIN-BASED FIBRES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2006-11-16 WO claimed
EP-1715839-A1 AGENTS FOR COLOURING FIBRES CONTAINING KERATIN, COMPRISING HETEROCYCLIC ENAMINES AND REACTIVE CARBONYL COMPOUNDS AND/OR REACTION PRODUCTS THEREOF Henkel Kommanditgesellschaft auf Aktien (DE) 2006-11-02 EP claimed
WO-2006077039-A1 AGENTS FOR DYING KERATIN FIBERS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2006-07-27 WO claimed
WO-2006040015-A1 AGENT FOR COLOURING FIBRES CONTAINING KERATIN HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2006-04-20 WO claimed
WO-2006029687-A1 SUBSTANCE FOR DYEING KERATINIC FIBERS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2006-03-23 WO claimed
WO-2006029672-A1 PRODUCTS FOR DYEING KERATIN FIBERS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2006-03-23 WO claimed
WO-2005120445-A2 MEANS FOR COLOURING KERATIN-CONTAINING FIBRES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2005-12-22 WO claimed
WO-2005063178-A1 AGENTS FOR COLOURING FIBRES CONTAINING KERATIN, COMPRISING HETEROCYCLIC ENAMINES AND REACTIVE CARBONYL COMPOUNDS AND/OR REACTION PRODUCTS THEREOF HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2005-07-14 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220257483-A1 INCREASING THE STABILITY OF AGENTS FOR TREATING KERATIN MATERIAL KRT18, VIM, CDH1 ALDH1A1 143/4885TDP1 3850/4885KDM4E 344/4885
US-11918671-B2 Multi-tone hair dyeing method in three steps TYR, HAO2, HAAO ALDH1A1 111/4885TDP1 1532/4885KDM4E 1526/4885
US-20230031764-A1 MULTI-TONE HAIR DYEING METHOD IN THREE STEPS TYR, HAO2, HAAO ALDH1A1 111/4885TDP1 1532/4885KDM4E 1526/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.