SCHEMBL5355474

SCHEMBL5355474

COc1cc(C)c(C=O)cc1O

nearest known ligand 0.53

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 11/20 0.53
ALDH1A1 P00352 4/20 0.50
TDP1 Q9NUW8 2/20 0.50
TRIM24 O15164 2/20 0.50
TRIM33 Q9UPN9 2/20 0.50
AOX1 Q06278 1/20 0.50
HPGD P15428 1/20 0.50
ALDH5A1 P51649 1/20 0.50
ABAT P80404 1/20 0.50
KDM4E B2RXH2 1/20 0.48
TSHR P16473 1/20 0.48
TYR P14679 1/20 0.46
TLR2 O60603 1/20 0.46
TLR1 Q15399 1/20 0.46
TLR6 Q9Y2C9 1/20 0.46
CGAS Q8N884 1/20 0.44
PRKDC P78527 1/20 0.44
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29953159 1.00 ERN1 (0.53) ERN1ALDH1A1TDP1TRIM24TRIM33
SCHEMBL286553 0.92 ALDH1A1 (0.53) ERN1ALDH1A1TDP1TRIM24TRIM33
SCHEMBL5361924 0.84 ALDH1A1 (0.69) ERN1ALDH1A1TDP1TRIM24TRIM33
SCHEMBL6234401 0.84 ERN1 (0.53) ERN1ALDH1A1TDP1TRIM24TRIM33
SCHEMBL1494078 0.84 ALDH1A1 (0.68) ERN1ALDH1A1TDP1HPGDKDM4E
SCHEMBL29818672 0.82 ALDH1A1 (0.65) ERN1ALDH1A1TDP1HPGDKDM4E
SCHEMBL282147 0.82 ALDH1A1 (0.54) ERN1ALDH1A1TDP1HPGDKDM4E
SCHEMBL1004432 0.80 ALDH1A1 (0.57) ERN1ALDH1A1TDP1TRIM24TRIM33
SCHEMBL29459687 0.80 ALDH1A1 (0.57) ERN1ALDH1A1TDP1TRIM24TRIM33
SCHEMBL1002368 0.80 ALDH1A1 (0.69) ERN1ALDH1A1TDP1TRIM24TRIM33

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210289794-A1 COMPOSITIONS AND RELATED METHODS FOR AGRICULTURE FLAGSHIP PIONEERING INNOVATIONS V, INC. 2021-09-23 US disclosed
CN-106117392-A A kind of chitosan graft vanilloyl derivant and its preparation method and application 河南科技学院 2016-11-16 CN disclosed
CN-100478022-C Synergistic composition for treating hyperlipidemia COUNCIL SCIENT IND RES (IN) 2009-04-15 CN disclosed
US-20070027138-A1 Derivatives and analogs of galanthamine SANOCHEMIA PHARMAZEUTIKA AKTIENGESELLSCHAFT 2007-02-01 US disclosed
US-7166588-B2 Derivatives and analogs of galanthamine SANOCHEMIA PHARMAZEUTIKA AKTIENGESELLSCHAFT (AT) 2007-01-23 US disclosed
US-7166588-B2 Derivatives and analogs of galanthamine SANOCHEMIA PHARMAZEUTIKA AKTIENGESELLSCHAFT (AT) 2007-01-23 US disclosed
US-7166588-B2 Derivatives and analogs of galanthamine SANOCHEMIA PHARMAZEUTIKA AKTIENGESELLSCHAFT (AT) 2007-01-23 US disclosed
CN-1893965-A Synergistic composition for treating hyperlipemia COUNCIL SCIENT IND RES (IN) 2007-01-10 CN disclosed
US-6989165-B2 Synergistic composition for treating hyperilipdemia COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2006-01-24 US disclosed
WO-2005070442-A1 A SYNERGISTIC COMPOSITION FOR TREATING HYPERLIPIDEMIA COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2005-08-04 WO disclosed
US-20050136138-A1 Synergistic composition for treating hyperilipdemia COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2005-06-23 US disclosed
EP-1181294-B1 NOVEL DERIVATIVES AND ANALOGUES OF GALANTHAMIN SANOCHEMIA PHARMAZEUTIKA AG (AT) 2004-03-31 EP disclosed
EP-1181294-A1 NOVEL DERIVATIVES AND ANALOGUES OF GALANTHAMIN Sanochemia Pharmazeutika Aktiengesellschaft (AT) 2002-02-27 EP disclosed
WO-2001074820-A1 NOVEL DERIVATIVES AND ANALOGUES OF GALANTHAMIN SANOCHEMIA PHARMAZEUTIKA AKTIENGESELLSCHAFT (AT) 2001-10-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070027138-A1 Derivatives and analogs of galanthamine GALR2, GALR1, GALR3 ERN1 4264/4885ALDH1A1 2196/4885TDP1 2822/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.