Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP1 | P22413 | 2/20 | 0.48 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | PRNP | P04156 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28676590 | 1.00 | ENPP1 (0.48) | ENPP1ENPP3ALDH1A1KDM4EKMT2A | |
| SCHEMBL31636847 | 0.84 | ENPP3 (0.46) | ENPP1ENPP3ALDH1A1KDM4EKMT2A | |
| SCHEMBL24373483 | 0.81 | ALDH1A1 (0.37) | ENPP1ALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL30774158 | 0.81 | ALDH1A1 (0.37) | ENPP1ALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL30774201 | 0.81 | ALDH1A1 (0.50) | ALDH1A1KDM4EKMT2AMEN1HPGD | |
| SCHEMBL18264128 | 0.81 | ALDH1A1 (0.50) | ALDH1A1KDM4EKMT2AMEN1HPGD | |
| SCHEMBL9794609 | 0.81 | KDM4E (0.39) | ALDH1A1KDM4EKMT2AMEN1HPGD | |
| SCHEMBL25805404 | 0.78 | L3MBTL1 (0.34) | ENPP1ENPP3ALDH1A1KMT2AMEN1 | |
| SCHEMBL24373525 | 0.77 | KDM4E (0.51) | ALDH1A1KDM4EKMT2AMEN1HPGD | |
| SCHEMBL29479071 | 0.77 | KDM4E (0.51) | ALDH1A1KDM4EKMT2AMEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113637005-B | KRAS inhibitors for cancer treatment | 泰励生物科技（上海）有限公司 | 2024-05-24 | — | — | CN | disclosed |