Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Trifluoroacetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGK1 | P00558 | 2/20 | 0.35 |
| ▸ | PGK2 | P07205 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | PEPD | P12955 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL2728008 | 0.94 | PGK1 (0.38) | PGK1PGK2ALDH1A1PTPN1L3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL28679728 | 0.88 | ALDH1A1 (0.35) | PGK1PGK2ALDH1A1PTPN1L3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL9701047 | 0.87 | ALDH1A1 (0.40) | ALDH1A1L3MBTL1THRBTSHRCA2 | |
| Trifluoroacetic Acid SCHEMBL4430504 | 0.84 | PGK1 (0.36) | PGK1PGK2ALDH1A1PTPN1L3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL7814389 | 0.79 | ALDH1A1 (0.44) | ALDH1A1L3MBTL1THRBTSHRMEN1 | |
| Oxalic Acid SCHEMBL1573557 | 0.79 | BLM (0.41) | THRBPEPDTSHRMEN1LMNA | |
| Trifluoroacetic Acid SCHEMBL4598430 | 0.79 | — | — | |
| Oxalic Acid SCHEMBL7055254 | 0.79 | BLM (0.41) | THRBPEPDTSHRMEN1LMNA | |
| Trifluoroacetic Acid SCHEMBL2484766 | 0.79 | ALDH1A1 (0.44) | ALDH1A1L3MBTL1THRBTSHRMEN1 | |
| Trifluoroacetic Acid SCHEMBL474 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107615556-B | Electrolyte and metal hydride battery | 巴斯夫公司 | 2021-11-02 | — | — | CN | disclosed |