Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | MET | P08581 | 3/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.51 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29077341 | 0.90 | SMN1; SMN2 (0.60) | KMT2ATSHRRXFP1ALDH1A1HPGD | |
| SCHEMBL30575488 | 0.82 | RAB9A (0.63) | KMT2ARXFP1ALDH1A1THRBKCNK3 | |
| SCHEMBL17502599 | 0.79 | ALDH1A1 (0.62) | KMT2ATSHRALDH1A1HPGDMEN1 | |
| SCHEMBL3455356 | 0.77 | HTT (0.66) | KMT2ATSHRALDH1A1HPGDKCNK3 | |
| SCHEMBL17502721 | 0.75 | MEN1 (0.59) | KMT2ATSHRALDH1A1HPGDMEN1 | |
| SCHEMBL28652995 | 0.75 | MEN1 (0.65) | KMT2ATSHRALDH1A1MEN1TP53 | |
| SCHEMBL30575480 | 0.75 | MEN1 (0.65) | KMT2ATSHRALDH1A1MEN1TP53 | |
| SCHEMBL28640838 | 0.75 | MAPK1 (0.70) | KMT2ATSHRALDH1A1HPGDKCNK3 | |
| SCHEMBL28638516 | 0.75 | NPC1 (0.67) | KMT2ATSHRALDH1A1HPGDTHRB | |
| SCHEMBL17502663 | 0.74 | MEN1 (0.62) | KMT2ATSHRALDH1A1HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112812077-B | Benzamide compound, preparation method thereof, pharmaceutical composition and application | 中国科学院上海药物研究所 | 2023-08-22 | — | — | CN | disclosed |
| CN-112812077-A | Benzamide compound and preparation method, pharmaceutical composition and application thereof | 中国科学院上海药物研究所 | 2021-05-18 | — | — | CN | disclosed |