Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 1/20 | 0.51 |
| ▸ | PRMT5 | O14744 | 15/20 | 0.51 |
| ▸ | WDR77 | Q9BQA1 | 12/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28654413 | 1.00 | CARM1 (0.51) | CARM1PRMT5WDR77MEN1KMT2A | |
| SCHEMBL28656457 | 0.90 | POLB (0.48) | CARM1POLB | |
| SCHEMBL28656456 | 0.90 | POLB (0.48) | CARM1POLB | |
| SCHEMBL28673309 | 0.84 | PRMT5 (0.43) | PRMT5WDR77 | |
| SCHEMBL28673307 | 0.84 | PRMT5 (0.43) | PRMT5WDR77 | |
| SCHEMBL28670701 | 0.81 | DRD2 (0.53) | CARM1PRMT5WDR77POLB | |
| SCHEMBL18212446 | 0.76 | CARM1 (0.57) | CARM1PRMT5WDR77MEN1KMT2A | |
| SCHEMBL30304699 | 0.76 | CARM1 (0.66) | CARM1PRMT5WDR77MEN1KMT2A | |
| SCHEMBL28655189 | 0.76 | CARM1 (0.57) | CARM1PRMT5WDR77MEN1KMT2A | |
| SCHEMBL28057284 | 0.76 | CARM1 (0.66) | CARM1PRMT5WDR77MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107735088-B | Histone deacetylase inhibitors, compositions and methods of use thereof | CHDI基金会股份有限公司 | 2021-11-02 | — | — | CN | disclosed |